Cellvento® ModiFeed Prime COMP is a highly concentrated, one-part, pH neutral feed added to replenish depleted nutrients required for cellular function and to extend the production phase in fed-batch mode. This single feed is highly concentrated, allowing for a reduction in volume of feed added to the medium thereby increasing product yield.The formulation has been specifically designed to provide increased process control and decreased complexity. Exclusion of glucose from the formulation allows for fed-batch process dictated regulation of this critical parameter. As a one-part feed, containing modified amino acids and amino acid derivatives, the complexity of hydration, storage, and feeding is drastically reduced.
Cellvento® ModiFeed Prime COMP has been developed as a feed supplement to be used in combination with the production media, Cellvento® 4CHO COMP and EX-CELL® Advanced CHO, during fed-batch manufacturing processes. It has been designed to support optimal cell growth and high productivity of suspension CHO cell lines such as CHO-K1, CHO-DG44, CHO-S and CHO-GS, including cell lines derived using the CHOZN® platform
Fed-batch (batch, perfusion)
Features and Benefits
The option to store hydrated feed protected from light at either at 2-8°C for up to 90 days or room temperature for up to 30 days provides unparallel flexibility.
Submit the Cellvento CHO request form to get in touch with a SAFC representative. Submit the EX-CELL Advanced CHO Fed-batch request form to get in touch with a SAFC representative: "http://go.sigmaaldrich.com/cho_fed_batch"
See product information sheet.
CELLVENTO is a registered trademark of Merck KGaA, Darmstadt, Germany
CHOZN is a registered trademark of Sigma-Aldrich Co. LLC
EX-CELL is a registered trademark of Sigma-Aldrich Co. LLC
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany