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142387

Sigma-Aldrich

2,4,6-Trimethylpyridine

ReagentPlus®, 99%

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Synonym(s):
2,4,6-Collidine, sym-Collidine
Empirical Formula (Hill Notation):
C8H11N
CAS Number:
Molecular Weight:
121.18
Beilstein:
107283
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

Quality Level

product line

ReagentPlus®

Assay

99%

form

liquid

refractive index

n20/D 1.498 (lit.)

bp

171-172 °C (lit.)

mp

−43 °C (lit.)

density

0.917 g/mL at 25 °C (lit.)

SMILES string

Cc1cc(C)nc(C)c1

InChI

1S/C8H11N/c1-6-4-7(2)9-8(3)5-6/h4-5H,1-3H3

InChI key

BWZVCCNYKMEVEX-UHFFFAOYSA-N

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1 of 4

This Item
2769065663128612
2,4,6-Trimethylpyridine ReagentPlus®, 99%

142387

2,4,6-Trimethylpyridine

2,4,6-Trimethylpyridine puriss. p.a., 99% (GC)

27690

2,4,6-Trimethylpyridine

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

100

refractive index

n20/D 1.498 (lit.)

refractive index

n20/D 1.498 (lit.)

refractive index

-

refractive index

-

form

liquid

form

liquid

form

-

form

-

bp

171-172 °C (lit.)

bp

171-172 °C (lit.)

bp

-

bp

-

mp

−43 °C (lit.)

mp

−43 °C (lit.)

mp

280-286 °C

mp

-

General description

2,4,6-Trimethylpyridine is a pyridine derivative. It has a pK of 7.4. The product can react with trifluoroiodomethane in cyclopentane solution to afford 1:1 complex. This complex was investigated by NMR (Nuclear Magnetic Resonance) spectroscopy. Collidine-buffered osmium tetroxide solutions have been prepared by adding osmium tetroxide solution to it. These solutions have been used as fixative for electron microscopic studies.
2,4,6-Trimethylpyridine can undergo oxidation with potassium permanganate to form 2,4,6-pyridinetricarboxylic acid.
Hindered base.

Application

2,4,6-Trimethylpyridine (collidine, s-collidine, 2,4,6-collidine) has been used in the preparation of a library of N-acyl aminocoumarins bearing low-molecular-weight N-acyl groups.
Useful solvent for the cleavage of hindered esters by anhydrous lithium iodide.
Tissue fixative for electron microscopy.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

FlameSkull and crossbones

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

131.0 °F - closed cup

Flash Point(C)

55 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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[60]fullerene has been shown to form 1:1 molecular complexes with pyridine and some methylated pyridines such as 2-picoline, 3-picoline, 4-picoline, 2,6-lutidine and 2,4,6-collidine in CCl4 medium by absorption spectrometric method. Well defined charge transfer (CT) bands have been observed for

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