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C5743

Sigma-Aldrich

Cilastatin sodium salt

≥98% (HPLC)

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Synonym(s):
Cilastatin sodium
Empirical Formula (Hill Notation):
C16H25N2NaO5S
CAS Number:
81129-83-1
Molecular Weight:
380.43
EC Number:
279-694-4

biological source

synthetic (organic)

Quality Level

100

Assay

≥98% (HPLC)

form

powder

solubility

water: 10 mg/mL, clear, colorless to faintly yellow

storage temp.

2-8°C

InChI

1S/C16H26N2O5S.Na/c1-16(2)8-10(16)13(19)18-12(15(22)23)6-4-3-5-7-24-9-11(17)14(20)21;/h6,10-11H,3-5,7-9,17H2,1-2H3,(H,18,19)(H,20,21)(H,22,23);/q;+1/p-1/b12-6-;/t10-,11+;/m1./s1

InChI key

QXPBTTUOVWMPJN-QBNHLFMHSA-M

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This Item
C2170000SML0005M4531
Sigma-Aldrich

Sigma-Aldrich

C5743

Cilastatin sodium salt

vibrant-m

C2170000

Cilastatin sodium

Cerivastatin sodium salt hydrate ≥98% (HPLC)

Sigma-Aldrich

SML0005

Cerivastatin sodium salt hydrate

Meclofenamic acid sodium salt

Sigma-Aldrich

M4531

Meclofenamic acid sodium salt

assay

≥98% (HPLC)

assay

-

assay

≥98% (HPLC)

assay

≥93% (HPLC)

form

powder

form

-

form

powder

form

powder

solubility

water: 10 mg/mL, clear, colorless to faintly yellow

solubility

-

solubility

H2O: ≥5 mg/mL

solubility

water: 50 mg/mL, clear, colorless to faintly brownish-yellow, water: 50 mg/mL, clear, colorless to faintly yellow, water: 50 mg/mL, clear, colorless to very faintly brown

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

storage temp.

-

General description

Cilastatin sodium salt is off-white to yellowish-white, hygroscopic, amorphous compound. It is derivatized from heptenoic acid. Its molecular mass is 380.43 g.

Biochem/physiol Actions

Inhibitor of the renal enzyme dehydropeptidase I and some bacterial zinc-containing β-lactamases. By these action, cilastatin suppresses both host and target metabolism of the broad-spectrum antibiotic imipenem, improving its efficacy.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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