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N6136

Sigma-Aldrich

Nickel(II) chloride hexahydrate

BioReagent, suitable for cell culture

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Synonym(s):
NiCl2.6H2O, Nickel chloride hexahydrate, Nickel dichloride hexahydrate
Linear Formula:
NiCl2 · 6H2O
CAS Number:
Molecular Weight:
237.69
MDL number:
PubChem Substance ID:
NACRES:
NA.71

product line

BioReagent

Quality Level

form

powder

technique(s)

cell culture | mammalian: suitable

SMILES string

[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].Cl[Ni]Cl

InChI

1S/2ClH.Ni.6H2O/h2*1H;;6*1H2/q;;+2;;;;;;/p-2

InChI key

LAIZPRYFQUWUBN-UHFFFAOYSA-L

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1 of 4

This Item
22338731462451193
Nickel(II) chloride hexahydrate BioReagent, suitable for cell culture

N6136

Nickel(II) chloride hexahydrate

Essential+ Grade
Nickel(II) chloride hexahydrate ReagentPlus®

223387

Nickel(II) chloride hexahydrate

-
Nickel(II) chloride hexahydrate puriss. p.a., ≥98%

31462

Nickel(II) chloride hexahydrate

-
Nickel(II) chloride anhydrous, powder, 99.99% trace metals basis

451193

Nickel(II) chloride

-
Quality Level

200

Quality Level

100, 200

Quality Level

200

Quality Level

200

product line

BioReagent

product line

ReagentPlus®

product line

-

product line

-

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

-

technique(s)

-

redoxing cation, enzyme cofactor, F430, urease

-

-

-

Application

Nickel(II) chloride hexahydrate has been used:
  • in the preparation of nickel platting solution for galvanostatically coating nickel inside the reduced carbon layer during the synthesis of multiwall carbon nanotube micromotors
  • in screening of metals for inflammatory effect on vascular endothelial cells
  • as an additive in artificial cerebrospinal fluid (ACSF) to analyse excitatory post synaptic currents (EPSPs) in the hippocampus slices

Biochem/physiol Actions

Nickel (Ni) is an essential trace element that plays an important role in the structure and function of DNA, RNA and protein. It has toxic effects on renal, pulmonary and cardiovascular system at higher concentrations. Nickel is implicated in carcinogenesis. Ni2+ ions is a clastogenic agent. Nickel ions (Ni2+) is a non-specific voltage-gated calcium channel blocker.

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A Inhalation - Muta. 2 - Repr. 1B - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1 Inhalation

Target Organs

Lungs

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Salnikow K and Zhitkovich A
Chemical Research in Toxicology, 21(1), 28-44 (2007)
Nonrandom chromosomal alterations in nickel-transformed Chinese hamster embryo cells
Conway K and Costa M
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Surfactant-Free beta-Galactosidase Micromotors for ?On-The-Move? Lactose Hydrolysis
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