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P2263

Sigma-Aldrich

Polyethyleneglycol Bisphenol A Epichlorohydrin Copolymer

mol wt 15,000-20,000 Da

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Synonym(s):
Polyethylene glycol compound
Linear Formula:
[C15H16O2·C3H5ClO·(C2H4O)n·H2O]x
CAS Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

form

flakes

Quality Level

mol wt

15,000-20,000 Da

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This Item
20250981323405493
Poly(ethylene glycol) methyl ether average Mn ~2,000

202509

Poly(ethylene glycol) methyl ether

Poly(ethylene glycol) methyl ether average Mn 5,000

81323

Poly(ethylene glycol) methyl ether

form

flakes

form

flakes (or pellets)

form

flakes, powder or crystals

form

liquid

mol wt

15,000-20,000 Da

mol wt

average Mn ~2,000

mol wt

average Mn 5,000

mol wt

average Mn ~377

General description

Polyethyleneglycol bisphenol A epichlorohydrin copolymer is a polyethylene glycol compound that has been shown to protect the intestinal epithelium against microbial invasion during stress.

Application

Polyethyleneglycol bisphenol A epichlorohydrin copolymer has been used on glioma cells to compare therapeutic strategies for malignant gliomas.

Preparation Note

Consists of 2 molecules of polyethylene glycol (mol. wt. 7,000-9,000) joined internally through a homobifunctional aromatic spacer.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Licheng Wu et al.
Gastroenterology, 126(2), 488-498 (2004-02-06)
During stress, erosion of protective intestinal mucus occurs in association with adherence to and disruption of the intestinal epithelial barrier by invading opportunistic microbial pathogens. The aims of this study were to test the ability of a high-molecular-weight polyethylene glycol
William N Batts et al.
Virus research, 230, 38-49 (2017-01-16)
A novel virus, rainbow trout orthomyxovirus (RbtOV), was isolated in 1997 and again in 2000 from commercially-reared rainbow trout (Oncorhynchus mykiss) in Idaho, USA. The virus grew optimally in the CHSE-214 cell line at 15°C producing a diffuse cytopathic effect;
Shigeru Yamaguchi et al.
Ultrasonics sonochemistry, 18(5), 1197-1204 (2011-01-25)
Sonodynamic therapy is expected to be a novel therapeutic strategy for malignant gliomas. The titanium dioxide (TiO(2)) nanoparticle, a photosensitizer, can be activated by ultrasound. In this study, by using water-dispersed TiO(2) nanoparticles, an in vitro comparison was made between
Shigeru Yamaguchi et al.
Photochemistry and photobiology, 86(4), 964-971 (2010-05-25)
Titanium dioxide (TiO(2)) is thought to be a photocatalytic agent excited by UV light. Our aim was to investigate the photocatalytic antitumor effect of water-dispersed TiO(2) nanoparticles on C6 rat glioma cells and to evaluate the treatment responses by the
Sangheon Han et al.
Biomedical optics express, 10(7), 3472-3483 (2019-07-31)
Gold nanoparticles (AuNPs) below 10 nm in size can undergo renal clearance, which could facilitate their clinical translation. However, due to non-linear, direct relationship between their absorption and size, use of such "ultra-small" AuNPs as contrast agents for photoacoustic imaging

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