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R7017

Sigma-Aldrich

Resazurin sodium salt

powder, BioReagent

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Synonym(s):
7-Hydroxy-3H-phenoxazin-3-one-10-oxide sodium salt
Empirical Formula (Hill Notation):
C12H6NNaO4
CAS Number:
62758-13-8
Molecular Weight:
251.17
Beilstein:
3794971
EC Number:
263-718-5
MDL number:
MFCD00005036
PubChem Substance ID:
24899387
NACRES:
NA.75

product line

BioReagent

Quality Level

200

form

powder

composition

Dye content, ~80%

pH

3.8-6.5, orange to violet

solubility

H2O: soluble

λmax

600 nm

SMILES string

[Na+].[O-]c1ccc2c(OC3=CC(=O)C=CC3=[N+]2[O-])c1

InChI

1S/C12H7NO4.Na/c14-7-1-3-9-11(5-7)17-12-6-8(15)2-4-10(12)13(9)16;/h1-6,14H;/q;+1/p-1

InChI key

IVGPGQSSDLDOLH-UHFFFAOYSA-M

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This Item
R2886199303R3257
Resazurin sodium salt powder, BioReagent

Sigma-Aldrich

R7017

Resazurin sodium salt

Resorufin β-D-glucuronide sodium salt ≥90%

Sigma-Aldrich

R2886

Resorufin β-D-glucuronide sodium salt

Resazurin sodium salt certified by the Biological Stain Commission

Sigma-Aldrich

199303

Resazurin sodium salt

Resorufin sodium salt redox indicator

Sigma-Aldrich

R3257

Resorufin sodium salt

pH

3.8-6.5, orange to violet

pH

-

pH

-

pH

-

solubility

H2O: soluble

solubility

water: 0.5 mg/mL, clear to slightly hazy, orange

solubility

1 M NH4OH: 1 mg/mL

solubility

water: 1 mg/mL, opaque

product line

BioReagent

product line

-

product line

-

product line

-

composition

Dye content, ~80%

composition

-

composition

Dye content, 75%

composition

-

λmax

600 nm

λmax

-

λmax

380 nm (2nd), 598 nm

λmax

-

Application

Resazurin sodium salt has been used in viability assay:
  • to measure cell viability of A. fumigatus
  • to assess cell proliferation
  • to determine A. fumigatus viability in high-throughput screenings of microbial natural extracts

For the measurement of metabolic activity and proliferation of living cells. The bioreduction of the dye reduces the amount of the oxidized form (blue) and concomitantly increases the fluorescent intermediate (red).

Biochem/physiol Actions

Resazurin is a blue, non-fluorescent dye originally used to test milk/biological fluids for bacterial and yeast contamination. It is also useful in sperm viability and semen quality test. Resazurin is applicable in cytotoxicity determination.

related product

Product No.
Description
Pricing

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315 - H319 - H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Expression of TweakR in breast cancer and preclinical activity of enavatuzumab, a humanized anti-TweakR mAb
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