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D5146

Sigma-Aldrich

Diazolidinyl urea

≥95%

Empirical Formula (Hill Notation):
C8H14N4O7
CAS Number:
Molecular Weight:
278.22
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥95%

form

powder

storage temp.

2-8°C

SMILES string

OCNC(=O)N(CO)C1N(CO)C(=O)N(CO)C1=O

InChI

1S/C8H14N4O7/c13-1-9-7(18)10(2-14)5-6(17)12(4-16)8(19)11(5)3-15/h5,13-16H,1-4H2,(H,9,18)

InChI key

SOROIESOUPGGFO-UHFFFAOYSA-N

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This Item
D4879554693226106
Diazolidinyl urea ≥95%

Sigma-Aldrich

D5146

Diazolidinyl urea

(2-Hydroxyethyl)urea 95%

Sigma-Aldrich

554693

(2-Hydroxyethyl)urea

form

powder

form

powder

form

solid

form

powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

-

General description

Diazolidinyl urea is urea derivative that is commonly used as a preservative and antimicrobial agent in cosmetics and personal care products.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Determination of diazolidinyl urea in a topical cream by high-performance liquid chromatography
Williams III, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 696, 303-306 (1997)
Erythrocyte Toxicities of Imidazolidinyl Urea and Diazolidinyl Urea
Noureddine H, et al.
Journal of Materials Science and Engineering. B, 3(7B), 445-445 (2013)
Diazolidinyl urea: incidence of sensitivity, patterns of cross?reactivity and clinical relevance.
Hectorne KJ & Fransway AF
Contact Dermatitis, 30(1), 16-19 (1994)
A T Karlberg et al.
Contact dermatitis, 38(1), 20-28 (1998-03-21)
Reliable and uncomplicated methods for detection of free formaldehyde in products preserved with formaldehyde donors are desirable to decrease the risk of allergic contact dermatitis. The aim of this study was to develop a method that could be used in
Claus Zachariae et al.
Contact dermatitis, 53(5), 268-277 (2005-11-15)
The elicitation potential of the cosmetic preservative diazolidinyl urea was studied in formaldehyde- and diazolidinyl urea-sensitized volunteer patients using a stepwise controlled exposure design. The test product was a facial moisturizer, preserved with varying concentrations of diazolidinyl urea, ranging from

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