1.07427

Propyl 4-hydroxybenzoate

EMPROVE^® ESSENTIAL, Ph. Eur., BP, JP, NF

• Synonym(s): Propyl 4-hydroxybenzoate, Propylparaben
• Empirical Formula (Hill Notation): C₁₀H₁₂O₃
• CAS Number: 94-13-3
• Molecular Weight: 180.20
• MDL number: MFCD00002354
• EC Index Number: 202-307-7

Properties

• Agency: BP; JP; NF; Ph. Eur.
• Quality Level: 500
• vapor pressure: 0.67 hPa ( 122 °C)
• product line: EMPROVE^® ESSENTIAL
• form: solid
• autoignition temp.: >600 °C
• potency: >5000 mg/kg LD₅₀, oral (Rat)
• pH: 6-7 (20 °C in H₂O, saturated solution)
• mp: 96-98 °C
• transition temp: flash point 180 °C
• solubility: 0.4 g/L
• density: 1.063 g/cm³ at 102 °C
• application(s): liquid formulation; ophthalmics; parenterals; pharmaceutical; semi-solid formulation; solid formulation
• storage temp.: 15-25°C
• InChI: 1S/C10H12O3/c1-2-7-13-10(12)8-3-5-9(11)6-4-8/h3-6,11H,2,7H2,1H3
• InChI key: QELSKZZBTMNZEB-UHFFFAOYSA-N

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Propyl 4-hydroxybenzoate has antimicrobial characteristics and is used as preservative in pharmaceutical formulations and cosmetics. It can be combined with other parabens like methyl 4-hydroxybenzoate or ethyl 4-hydroxybenzoate.

Packaging

5 kg in PE drum

25 kg in double PE bag (DPES in carton)

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): 356.0 °F
• Flash Point(C): 180 °C