1.07428

Propyl 4-hydroxybenzoate sodium salt

EMPROVE^® ESSENTIAL, Ph. Eur., BP, NF

• Synonym(s): Propyl 4-hydroxybenzoate sodium salt, 4-Hydroxybenzoic acid propyl ester sodium salt, Propylparaben sodium salt
• Empirical Formula (Hill Notation): C₁₀H₁₁NaO₃
• CAS Number: 35285-69-9
• Molecular Weight: 202.18
• MDL number: MFCD00016477
• EC Index Number: 252-488-1

Properties

• Agency: BP; NF; Ph. Eur.
• Quality Level: 500
• product line: EMPROVE^® ESSENTIAL
• form: solid
• pH: 9.5-10.5 (20 °C, 1 g/L in H₂O)
• mp: 302 °C
• density: 1.24 g/cm³ at 25 °C
• application(s): liquid formulation; ophthalmics; pharmaceutical; semi-solid formulation; solid formulation
• storage temp.: 15-25°C
• InChI: 1S/C10H12O3.Na/c1-2-7-13-10(12)8-3-5-9(11)6-4-8;/h3-6,11H,2,7H2,1H3;/q;+1/p-1
• InChI key: IXMINYBUNCWGER-UHFFFAOYSA-M

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Propyl 4-hydroxybenzoate has antimicrobial characteristics and is used as preservative in pharmaceutical formulations and cosmetics. It can be combined with other parabens like methyl 4-hydroxybenzoate or ethyl 4-hydroxybenzoate. The sodium salt provides improved solubility in water compared to standard propyl 4-hydroxybenzoate.

Packaging

5 kg in PE bottle

25 kg in double PE bag (DPES in carton)

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H318
• Precautionary Statements: P280 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3