PHR1106

L-Arginine

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(s): (S)-2-Amino-5-guanidinopentanoic acid
• Linear Formula: H₂NC(=NH)NH(CH₂)₃CH(NH₂)CO₂H
• CAS Number: 74-79-3
• Molecular Weight: 174.20
• NACRES: NA.24
• PubChem Substance ID: 329823128
• eCl@ss: 32160406
• UNSPSC Code: 41116107
• EC Number: 200-811-1
• MDL number: MFCD00002635
• Beilstein/REAXYS Number: 1725413

Properties

• Product Name: L-Arginine, Pharmaceutical Secondary Standard; Certified Reference Material
• InChI: 1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m0/s1
• InChI key: ODKSFYDXXFIFQN-BYPYZUCNSA-N
• SMILES string: N[C@@H](CCCNC(N)=N)C(O)=O
• grade: certified reference material; pharmaceutical secondary standard
• agency: traceable to Ph. Eur. A1270000; traceable to USP 1042500
• API family: arginine
• CofA: current certificate can be downloaded
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• mp: 222 °C (dec.) (lit.)
• application(s): cleaning products; cosmetics; flavors and fragrances; food and beverages; personal care; pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-30°C
• Quality Level: 300

Description

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. L-Arginine is a dibasic, semi-essential amino acid. It acts as a precursor for creatinine and is a natural constituent of most of the dietary proteins. It also plays a key role in many physiological processes such as tissue repair and reproduction.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAA7157 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable