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Merck

C1276

L-Cysteine hydrochloride

≥98% (TLC), suitable for UHPLC

Synonym(s):

(2R)-2-Amino-3-sulfanylpropanoic acid hydrochloride

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€97.00

50 G

€294.00

100 G

€505.00

250 G

€974.00

€97.00


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About This Item

Linear Formula:
HSCH2CH(NH2)COOH · HCl
CAS Number:
Molecular Weight:
157.62
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
200-157-7
MDL number:
Beilstein/REAXYS Number:
3560277

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Product Name

L-Cysteine hydrochloride, anhydrous, ≥98% (TLC)

InChI key

IFQSXNOEEPCSLW-DKWTVANSSA-N

InChI

1S/C3H7NO2S.ClH/c4-2(1-7)3(5)6;/h2,7H,1,4H2,(H,5,6);1H/t2-;/m0./s1

SMILES string

Cl[H].N[C@@H](CS)C(O)=O

grade

anhydrous

assay

≥98% (TLC)

form

powder

technique(s)

UHPLC: suitable

color

white

mp

174.1-174.7 °C

solubility

H2O: 50 mg/mL, clear, colorless

Quality Level

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1 of 4

This Item
30089C121908C7477
form

powder

form

powder or crystals

form

powder

form

powder or crystals

grade

anhydrous

grade

-

grade

-

grade

anhydrous

technique(s)

UHPLC: suitable

technique(s)

HPLC: suitable

technique(s)

-

technique(s)

cell culture | mammalian: suitable

assay

≥98% (TLC)

assay

≥98.5% (RT)

assay

98%

assay

≥98.0%

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

color

white

color

white

color

white

color

white to off-white

Application

L-Cysteine hydrochloride has been used as a supplement in media to study the metabolic and sleep phenotypes of Drosophila melanogaster.[1] It has also been used as one of the reagents for cell dissociation and single cell collection.[2]

Biochem/physiol Actions

Cysteine (Cys) is a functional sulfur-containing aminoacid that regulates metabolism for growth, reproduction and immunity. It provides the disulfide linkage in proteins and is involved in the transport of sulfur. Cysteine is involved in the formation of hydrogen sulfide that functions as a signaling molecule. Cys residues are present at the catalytic sites of various enzymes.[3][4]
NMDA glutamatergic receptor agonist that is also an agonist at AMPA glutamatergic receptors at high concentrations.
NMDA glutamatergic receptor agonist; AMPA glutamatergic receptor agonist at high concentrations.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Independent Effects of ?-Aminobutyric Acid Transaminase (GABAT) on Metabolic and Sleep Homeostasis
Sarah E. Maguire
The Journal of Biological Chemistry, 290 (2015)
Isolation of intact astrocytes from the optic nerve head of adult mice
Hee Joo Choi
Experimental Eye Research, 137, 103-110 (2015)
Richard S. Lord, J. Alexander Bralley
Laboratory Evaluations for Integrative and Functional Medicine (2008)
Justin Komguep Nono et al.
Frontiers in immunology, 11, 798-798 (2020-05-28)
Alveolar echinococcosis (AE), caused by the metacestode larval stage of the fox-tapeworm Echinococcus multilocularis, is a chronic zoonosis associated with significant modulation of the host immune response. A role of regulatory T-cells (Treg) in generating an immunosuppressive environment around the
Marc Y Fink et al.
Current protocols in microbiology, 57(1), e102-e102 (2020-06-10)
Giardia lamblia is a protozoan parasite that is found ubiquitously throughout the world and is a major contributor to diarrheal disease. Giardia exhibits a biphasic lifestyle existing as either a dormant cyst or a vegetative trophozoite. Infections are typically initiated

Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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