Merck
All Photos(3)

C4680

Sigma-Aldrich

α-Cyclodextrin

powder, BioReagent, suitable for cell culture, ≥98%

Synonym(s):
α-Schardinger dextrin, Cyclohexaamylose, Cyclomaltohexaose
Empirical Formula (Hill Notation):
C36H60O30
CAS Number:
Molecular Weight:
972.84
Beilstein:
79627
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.77

sterility

non-sterile

product line

BioReagent

Assay

≥98%

form

powder

technique(s)

cell culture | mammalian: suitable

mp

>278 °C (dec.) (lit.)

solubility

H2O: 10 mg/mL

shipped in

ambient

storage temp.

room temp

SMILES string

OC[C@H]1O[C@@H]2O[C@H]3[C@H](O)[C@@H](O)[C@H](O[C@@H]3CO)O[C@H]4[C@H](O)[C@@H](O)[C@H](O[C@@H]4CO)O[C@H]5[C@H](O)[C@@H](O)[C@H](O[C@@H]5CO)O[C@H]6[C@H](O)[C@@H](O)[C@H](O[C@@H]6CO)O[C@H]7[C@H](O)[C@@H](O)[C@H](O[C@@H]7CO)O[C@H]1[C@H](O)[C@H]2O

InChI

1S/C36H60O30/c37-1-7-25-13(43)19(49)31(55-7)62-26-8(2-38)57-33(21(51)15(26)45)64-28-10(4-40)59-35(23(53)17(28)47)66-30-12(6-42)60-36(24(54)18(30)48)65-29-11(5-41)58-34(22(52)16(29)46)63-27-9(3-39)56-32(61-25)20(50)14(27)44/h7-54H,1-6H2/t7-,8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-/m1/s1

InChI key

HFHDHCJBZVLPGP-RWMJIURBSA-N

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This Item
C464228705778788
α-Cyclodextrin powder, BioReagent, suitable for cell culture, ≥98%

Sigma-Aldrich

C4680

α-Cyclodextrin

α-Cyclodextrin ≥98%

Sigma-Aldrich

C4642

α-Cyclodextrin

α-Cyclodextrin purum, ≥98.0% (HPLC)

Sigma-Aldrich

28705

α-Cyclodextrin

α-Cyclodextrin produced by Wacker Chemie AG, Burghausen, Germany, ≥99.0% (HPLC)

Sigma-Aldrich

778788

α-Cyclodextrin

sterility

non-sterile

sterility

-

sterility

-

sterility

-

form

powder

form

powder

form

powder

form

solid

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

-

technique(s)

-

solubility

H2O: 10 mg/mL

solubility

H2O: 50 mg/mL

solubility

-

solubility

-

shipped in

ambient

shipped in

-

shipped in

-

shipped in

-

storage temp.

room temp

storage temp.

-

storage temp.

-

storage temp.

-

General description

α-Cyclodextrin (α-CD) is a cyclic oligosaccharide that consists of six glucopyranose units linked by α-(1,4) bonds. α-CD acts as a soluble dietary fiber and hence it is preferred to be widely used in food industry.

Application

Useful for the solubilization of nonpolar macromolecules such as fatty acids, lipids, and cholesterol for use in cell culture applications. α-Cyclodextrin has been used to solubilize odanacatib, a cathepsin K inhibitor.

Biochem/physiol Actions

α-Cyclodextrin is found to form a firm complex with dietary fats. This way it decreases the bioavailability and absorption of fats. It is known to regulate triglyceride and leptin levels in serum. In rat models, α-Cyclodextrin is shown to induce insulin sensitivity and fecal fat excretion. Thus, α-cyclodextrin is considered to be effective for treating obesity and metabolic syndromes.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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