108-86-1

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Showing 1-22 of 22 results for "108-86-1" within Papers

Molecular cloning and expression of aminopeptidase A isoforms from rat hippocampus.

H J Lee et al.

Biochimica et biophysica acta, 1493(1-2), 273-278 (2000-09-09)

The full-length cDNA encoding aminopeptidase A (APAL) was cloned from a rat hippocampus cDNA library. A short variant aminopeptidase A (APAS), produced by deletion, was also cloned. In the case of APAL, the longest open reading frame encodes 945 amino

K-ras mutations in lung tumors and tumors from other organs are consistent with a common mechanism of ethylene oxide tumorigenesis in the B6C3F1 mouse.

Hue-Hua L Hong et al.

Toxicologic pathology, 35(1), 81-85 (2007-02-28)

Ethylene oxide is a multisite carcinogen in rodents and classified as a human carcinogen by the National Toxicology Program. In 2-year mouse studies, ethylene oxide (EO) induced lung, Harderian gland (HG), and uterine neoplasms. We evaluated representative EO-induced and equivalent

Characterization of a cDNA clone encoding a new species of the nonspecific cross-reacting antigen (NCA), a member of the CEA gene family.

F Arakawa et al.

Biochemical and biophysical research communications, 166(3), 1063-1071 (1990-02-14)

To clarify the molecular structures of the nonspecific cross-reacting antigens (NCAs) produced by human granulocytes, we cloned cDNAs from libraries of normal white blood cells. A clone, NCA-W272, was found to code a protein similar to NCA of tumor cells.

Characterization of zinc-binding properties of a novel imidase from Pseudomonas putida YZ-26.

Ya-Wei Shi et al.

Archives of biochemistry and biophysics, 494(1), 1-6 (2009-11-26)

The imidase from Pseudomonas putida YZ-26 consisting of 293-amino acid residues is a novel imidase with four subunits as the holo-enzyme and low molecular weight which is significantly different from known mammalian imidase. This study measured the zinc-binding properties of

The N34S mutation of SPINK1 (PSTI) is associated with a familial pattern of idiopathic chronic pancreatitis but does not cause the disease.

J Threadgold et al.

Gut, 50(5), 675-681 (2002-04-16)

Mutations in the PRSS1 gene explain most occurrences of hereditary pancreatitis (HP) but many HP families have no PRSS1 mutation. Recently, an association between the mutation N34S in the pancreatic secretory trypsin inhibitor (SPINK1 or PSTI) gene and idiopathic chronic

Large-scale manufacturing of base-edited chimeric antigen receptor T cells.

Rosie Woodruff et al.

Molecular therapy. Methods & clinical development, 31, 101123-101123 (2023-10-27)

Base editing is a revolutionary gene-editing technique enabling the introduction of point mutations into the genome without generating detrimental DNA double-stranded breaks. Base-editing enzymes are commonly delivered in the form of modified linear messenger RNA (mRNA) that is costly to

A simple and fast method for chlorsulfuron and metsulfuron methyl determination in water samples using multiwalled carbon nanotubes (MWCNTs) and capillary electrophoresis.

Valeria H Springer et al.

Talanta, 83(1), 126-129 (2010-11-03)

A new method to determine metsulfuron methyl (MSM) and chlorsulfuron (CS) in different water samples was developed. It consists in a solid phase extraction (SPE) procedure using multiwalled carbon nanotubes (MWCNTs) as sorbent material in combination with capillary zone electrophoretic

Increased methionine sulfoxide content of apoA-I in type 1 diabetes.

Jonathan W C Brock et al.

Journal of lipid research, 49(4), 847-855 (2008-01-19)

Cardiovascular disease is a major cause of morbidity and premature mortality in diabetes. HDL plays an important role in limiting vascular damage by removing cholesterol and cholesteryl ester hydroperoxides from oxidized low density lipoprotein and foam cells. Methionine (Met) residues

Quantitative analysis of phenylalanine, tyrosine, tryptophan and kynurenine in rat model for tauopathies by ultra-high performance liquid chromatography with fluorescence and mass spectrometry detection.

Jaroslav Galba et al.

Journal of pharmaceutical and biomedical analysis, 117, 85-90 (2015-09-08)

We developed and validated a simple and sensitive ultra-high performance liquid chromatography (UHPLC) method for the analysis of phenylalanine (Phe), tyrosine (Tyr), tryptophan (Trp) and kynurenine (Kyn) in rat plasma. Analytes were separated on Acquity UPLC HSS T3 column (2.1

Source apportionment of ambient fine and coarse particulate matter polycyclic aromatic hydrocarbons at the Bertha Ganter-Fort McKay community site in the Oil Sands Region of Alberta, Canada.

Matthew S Landis et al.

The Science of the total environment, 666, 540-558 (2019-02-26)

A comprehensive filter-based particulate matter polycyclic aromatic hydrocarbon (PAH) source apportionment study was conducted at the Wood Buffalo Environmental Association Bertha Ganter-Fort McKay (BGFM) community monitoring station from 2014 to 2015 to quantify ambient concentrations and identify major sources. The

Surgical site infection prophylaxis strategies for cardiothoracic surgery: a decision-analytic model.

Keith S Kaye et al.

Scandinavian journal of infectious diseases, 44(12), 948-955 (2012-07-27)

Methicillin-resistant Staphylococcus aureus (MRSA) is a common cause of invasive surgical site infection (SSI) in the USA. Antimicrobial prophylaxis for SSI typically includes a cephalosporin. Vancomycin is used to provide MRSA coverage, but the timing of administration is challenging. Linezolid

Two-generation reproduction studies in Rats fed di-isodecyl phthalate.

L J Hushka et al.

Reproductive toxicology (Elmsford, N.Y.), 15(2), 153-169 (2001-04-12)

Di-isodecyl phthalate (DIDP) is a commercial plasticizer with low toxicity in many animal studies. The effects of dietary DIDP administration on fertility and developmental parameters were assessed in Sprague-Dawley rats utilizing two generation reproductive toxicity studies generally consistent with current

Performance evaluation of antibody tests for detecting infant respiratory syncytial virus infection.

Samadhan J Jadhao et al.

Journal of medical virology, 93(6), 3439-3445 (2020-12-17)

Respiratory syncytial virus (RSV) infection is a major cause of respiratory tract disease in young children and throughout life. Infant infection is also associated with later respiratory morbidity including asthma. With a prospective birth cohort study of RSV and asthma

A relationship between motilin and growth hormone secretagogue receptors.

Hiroaki Nunoi et al.

Regulatory peptides, 176(1-3), 28-35 (2012-04-03)

The motilin receptor (MR) belongs to a family of Class I G protein-coupled receptors that also includes growth hormone secretagogue receptor (GHSR). Their potentially unique structure and the molecular basis of their binding and activation are not yet clear. We

M1 Macrophages but Not M2 Macrophages Are Characterized by Upregulation of CRP Expression via Activation of NFκB: a Possible Role for Ox-LDL in Macrophage Polarization.

Marielle Kaplan et al.

Inflammation, 41(4), 1477-1487 (2018-04-25)

Arterial macrophages comprise a heterogeneous population: pro-inflammatory (M1) and anti-inflammatory (M2). Since C-reactive protein (CRP) is produced by macrophages in atherosclerotic lesions, understanding of CRP regulation in macrophages could be crucial to decipher inflammatory patterns in atherogenesis. We aimed to

Artificial Intelligence-Based Breast Cancer Nodal Metastasis Detection: Insights Into the Black Box for Pathologists.

Yun Liu et al.

Archives of pathology & laboratory medicine, 143(7), 859-868 (2018-10-09)

Nodal metastasis of a primary tumor influences therapy decisions for a variety of cancers. Histologic identification of tumor cells in lymph nodes can be laborious and error-prone, especially for small tumor foci. To evaluate the application and clinical implementation of

Quantification of ZAP70 mRNA in B cells by real-time PCR is a powerful prognostic factor in chronic lymphocytic leukemia.

Basile Stamatopoulos et al.

Clinical chemistry, 53(10), 1757-1766 (2007-08-19)

Chronic lymphocytic leukemia (CLL) is heterogeneous with respect to prognosis and clinical outcome. The mutational status of the immunoglobulin variable heavy chain region (IGHV) has been used to classify patients into 2 groups in terms of overall survival (OS) and

Analysis of Listeria monocytogenes strain distribution in a pork slaughter and cutting plant in the province of Quebec.

Guillaume Larivière-Gauthier et al.

Journal of food protection, 77(12), 2121-2128 (2014-12-05)

Following the 2008 Canadian listeriosis outbreak associated with ready-to-eat (RTE) meat products, regulations on the presence of Listeria monocytogenes in RTE food production facilities were modified by Health Canada, confirming the need to control this pathogen, not only in the

Ki-67 staining index predicts distant metastasis and survival in locally advanced prostate cancer treated with radiotherapy: an analysis of patients in radiation therapy oncology group protocol 86-10.

Rile Li et al.

Clinical cancer research : an official journal of the American Association for Cancer Research, 10(12 Pt 1), 4118-4124 (2004-06-26)

Proliferative activity defined by Ki-67 staining index (SI) has been correlated with progression and prognosis in a number of malignant tumors including prostate cancer. However, few studies have examined Ki-67 SI in pretreatment diagnostic material from patients treated with definitive

Daptomycin use in neutropenic patients with documented gram-positive infections.

Kenneth V I Rolston et al.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 22(1), 7-14 (2013-08-27)

The goal of this study was to describe the outcomes associated with daptomycin treatment of documented gram-positive infections in patients with neutropenia. All patients with neutropenia (≤500 cells/m(3)) and at least one documented gram-positive culture from 2006-2009 were identified from

Linkage of two human pregnancy-specific beta 1-glycoprotein genes: one is associated with hydatidiform mole.

K K Leslie et al.

Proceedings of the National Academy of Sciences of the United States of America, 87(15), 5822-5826 (1990-08-01)

A genomic clone containing two linked human pregnancy-specific beta 1-glycoprotein (PS beta G) genes has been isolated and characterized. The two genes are arranged in the same 5'----3' orientation; the 3' region (including the A2 and B-C exons) of the

Acute and subacute effects of tobacco alkaloids, tobacco-specific nitrosamines and phenethyl isothiocyanate on N'-nitrosonornicotine metabolism in rats.

Stefan Tyroller et al.

Toxicology, 215(3), 245-253 (2005-08-25)

N'-Nitrosonornicotine (NNN) was the first tobacco-specific nitrosamine (TSNA) identified as carcinogen in tobacco smoke, but no data exist on in vivo interactions between NNN and other tobacco alkaloids, TSNA or phenethyl isothiocyanate (PEITC) which have been demonstrated in various studies

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