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Showing 1-30 of 176 results for "56-55-3" within Papers
P González et al.
International journal of immunogenetics, 34(2), 127-130 (2007-03-22)
Arachidonate 5-lipoxygenase is an enzyme encoded by the ALOX5 gene, and plays an important role in the synthesis of leukotrienes. These are inflammatory mediators, and have been involved in atherosclerosis and other pathological processes that require proinflammatory activities. Human and
Zebalda D Bamji et al.
Anticancer research, 35(9), 4723-4732 (2015-08-09)
Prostate cancer is one of the leading causes of death in American males. Emetine, a naturally-derived alkaloid from the Ipecacuanha plant, has been shown to have potential for anti-tumorigenic effects for cancer treatments. The objective of this study was to
Maheshi N Ramasamy et al.
Lancet (London, England), 396(10267), 1979-1993 (2020-11-23)
Older adults (aged ≥70 years) are at increased risk of severe disease and death if they develop COVID-19 and are therefore a priority for immunisation should an efficacious vaccine be developed. Immunogenicity of vaccines is often worse in older adults
Koji Tsuta et al.
Pathology, research and practice, 208(8), 470-474 (2012-07-10)
The majority of neuroendocrine carcinomas (NECs) express somatostatin (SST) receptors (SSTRs). However, the expression of all 5 SSTR subtypes in pulmonary NECs has not been reported. We performed immunohistochemical analysis of all 5 SSTR subtypes (including the SSTR2A and 2B
N R Pumford et al.
Biochemical and biophysical research communications, 182(3), 1348-1355 (1992-02-14)
Acetaminophen is metabolized by cytochrome P450 to a reactive metabolite that covalently binds to proteins and this binding correlates with the hepatotoxicity. The major protein adduct was previously reported to be a 55 kDa protein that was detected on Western
M Tevfik Dorak et al.
The Journal of infectious diseases, 188(6), 856-863 (2003-09-10)
The human leukocyte antigen (HLA)-B22 serogroup--which consists of the alleles B*54, B*55, and B*56--has been associated with rapidly progressive disease in white patients with human immunodeficiency virus (HIV) infection. Subjects from 3 cohorts of men who have sex with men
Yeongsic Kim et al.
Annals of clinical and laboratory science, 40(3), 226-232 (2010-08-07)
Since PNH occasionally results in bone marrow failure, it is difficult to differentiate PNH from AA with small numbers of CD(55) (-)CD(59) (-) erythrocytes. We quantified CD55 and CD59 molecules expressed on normal reticulocytes and mature erythrocytes of paroxysmal nocturnal
Florence Teillet et al.
Journal of immunology (Baltimore, Md. : 1950), 178(9), 5710-5716 (2007-04-20)
Mannan-binding lectin (MBL) is an oligomeric lectin that binds neutral carbohydrates on pathogens, forms complexes with MBL-associated serine proteases (MASP)-1, -2, and -3 and 19-kDa MBL-associated protein (MAp19), and triggers the complement lectin pathway through activation of MASP-2. To identify
Brandie Heald et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 31(10), 1336-1340 (2013-02-13)
In 2009, the Evaluation of Genomic Applications in Practice and Prevention recommended that all colorectal cancers (CRCs) be screened for Lynch syndrome (LS) through microsatellite instability (MSI) or immunohistochemistry (IHC). No studies report how this process is implemented on a
Zhujun Zhang et al.
Journal of human genetics, 54(8), 466-473 (2009-07-18)
Duplications of one or more exons of the dystrophin gene are the second most common mutation in dystrophinopathies. Even though duplications are suggested to occur with greater complexity than thought earlier, they have been considered an intragenic event. Here, we
C K Hurley et al.
Tissue antigens, 52(1), 84-87 (1998-08-26)
Nine novel HLA-A and HLA-B alleles are described: A*2609, A*6803, A*6806, B*1539, B*1540, B*2712, B*4103, B*5109, and B*5603. Most appear to have arisen by gene conversion events. B*5603 appears to have arisen by a reciprocal recombination event joining exon 2
M Bagyánszki et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 23(6), e237-e248 (2011-04-08)
There are indications that alterations in the nitric oxide (NO) system of relaxation mediate gastrointestinal motor disturbances induced by chronic alcohol consumption (CAC). As CAC is known to inhibit the motility of the mouse small intestine, we investigated in this
Wendy T N Swelsen et al.
Human immunology, 66(5), 543-553 (2005-06-07)
More than 590 human leukocyte antigen (HLA)-B alleles have been identified by sequence analysis. Although the polymorphic exon 2 and 3 sequences of all HLA-B alleles are described, the sequences of the other exons of a number of infrequent B-alleles
M Bagyánszki et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 23(6), e237-e248 (2011-04-08)
There are indications that alterations in the nitric oxide (NO) system of relaxation mediate gastrointestinal motor disturbances induced by chronic alcohol consumption (CAC). As CAC is known to inhibit the motility of the mouse small intestine, we investigated in this
S Yanagi et al.
Journal of the National Cancer Institute, 73(4), 887-894 (1984-10-01)
A probably promoter-specific decrease of L-type pyruvate kinase (L-PK) in Wistar rat liver is described. The possibility of utilizing the decrease in L-PK activity for screening of hepatic promoters is discussed. A significantly decreased level of activity of L-PK was
B Stix et al.
The American journal of pathology, 159(2), 561-570 (2001-08-04)
We recently demonstrated the presence of matrix metalloproteinases (MMPs)-1, -2, and -3 in AA amyloid deposits, which lead us to speculate that MMPs may participate in amyloidogenesis by either processing the precursor protein, or by degrading the amyloid deposits. Here
Alan J McCubbin et al.
European journal of applied physiology, 119(9), 2105-2118 (2019-08-05)
To determine the impact of altering dietary sodium intake for 3 days preceding exercise on sweat sodium concentration [Na+], and cardiovascular and thermoregulatory variables. Fifteen male endurance athletes (runners n = 8, cyclists n = 7) consumed a low (LNa, 15 mg kg-1 day-1) or high (HNa, 100 mg kg-1 day-1)
Fan Lin et al.
The American journal of surgical pathology, 32(1), 78-91 (2007-12-29)
Recently, we demonstrated von Hippel-Lindau gene product (pVHL) was expressed in normal pancreatic ducts but absent in pancreatic ductal adenocarcinoma (PDA). Previous studies have suggested the diagnostic value of S100P, S100A4, and S100A6 in PDA. In this study, we evaluated
Ekhlas Qaid Gazem Othman et al.
Journal of clinical laboratory analysis, 23(4), 249-258 (2009-07-23)
Autophagy is a protein degradation process within the cell and its deregulation has been linked to various diseases and the formation of cancer. One of the important proteins involved in the autophagy process is microtubule-associated protein 1 light chain 3
H Ramaswamy et al.
The EMBO journal, 9(5), 1561-1568 (1990-05-01)
The originally described integrin beta subunits that define the three subfamilies of integrin heterodimers are beta 1, beta 2 and beta 3. In this paper, we describe the isolation of a cDNA coding for a novel human integrin beta subunit
H Ramaswamy et al.
The EMBO journal, 9(5), 1561-1568 (1990-05-01)
The originally described integrin beta subunits that define the three subfamilies of integrin heterodimers are beta 1, beta 2 and beta 3. In this paper, we describe the isolation of a cDNA coding for a novel human integrin beta subunit
Junko Fujihara et al.
Legal medicine (Tokyo, Japan), 9(5), 233-236 (2007-02-27)
Deoxyribonuclease I (DNase I) plays important roles for DNA fragmentation and degradation during programmed cell death. The single nucleotide polymorphism (SNP) at DNase I, designated as DNASE1, in exon 8 (A2317G) is considered to be one of the susceptibility genes
Erik Helgeland et al.
Scandinavian cardiovascular journal : SCJ, 49(5), 270-279 (2015-07-15)
It has previously been demonstrated that 15-min continuous insulin infusion at immediate reperfusion affords cardioprotection. This study sought to reduce the treatment time of insulin and test if intermittent insulin infusions can mimic ischemic postconditioning. In a Langendorff perfused rat
K E Djadou et al.
Medecine et sante tropicales, 22(3), 283-286 (2012-11-24)
To evaluate the monitoring of HIV-infected children receiving antiretroviral therapy in rural areas of Togo and the effectiveness of the treatment. This retrospective descriptive study, conducted at the Luis Scrosospi Center in Kouvé from 15 November, 2008, through 14 November
Imdad Ali et al.
Bioorganic chemistry, 100, 103937-103937 (2020-05-28)
In treating wounds, long lasting infection is considered the major impediment. Drugs are rendered ineffective by pathogenic microorganisms via antibiotic resistance and calls for designing and development of new drugs. Herein, we report synthesis of eight different N-alkylated pyridine-based organic
C L Sage et al.
The Journal of membrane biology, 185(2), 103-115 (2002-03-14)
K+ secretion by strial marginal cell and vestibular dark cell epithelia is regulated by UTP and ATP at both the apical and basolateral membranes, suggesting control by P2Y2 and/or P2Y4 purinergic receptors. Immunolocalization was used to determine the identity and
Daniel L Priebbenow et al.
Journal of medicinal chemistry, 63(9), 4655-4684 (2020-03-03)
A high-throughput screen designed to discover new inhibitors of histone acetyltransferase KAT6A uncovered CTX-0124143 (1), a unique aryl acylsulfonohydrazide with an IC50 of 1.0 μM. Using this acylsulfonohydrazide as a template, we herein disclose the results of our extensive structure-activity
G J Van Ommen et al.
Biochimie, 71(2), 211-221 (1989-02-01)
We have cloned the thyroglobulin (Tg) gene of normal goats and goitrous goats which have a Tg synthesis defect. At the 5'-end of the gene, we studied cosmid clones covering a region from 20 kilobases (kb) upstream from the Tg
H C Hsu et al.
Cancer research, 57(22), 5179-5184 (1997-11-26)
Using the differential display method to analyze mRNA expression in hepatocellular carcinoma (HCC) and nontumor livers, we cloned a full-length cDNA of 2263 bp, which was designated GTR2-2 and was identical with MXR7. The MXR7 mRNA was detected in 143
Marit Poffers et al.
Anesthesiology, 128(6), 1151-1166 (2018-03-07)
Voltage-gated sodium channels generate action potentials in excitable cells, but they have also been attributed noncanonical roles in nonexcitable cells. We hypothesize that voltage-gated sodium channels play a functional role during extravasation of neutrophils. Expression of voltage-gated sodium channels was
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