A8625

N-Acetyl-D-glucosamine

≥99%

• Synonym(s): 2-Acetamido-2-deoxy-D-glucose, D-GlcNAc
• Empirical Formula (Hill Notation): C₈H₁₅NO₆
• CAS Number: 7512-17-6
• Molecular Weight: 221.21
• Beilstein: 1727589
• EC Number: 231-368-2
• MDL number: MFCD00061615
• PubChem Substance ID: 24891348
• NACRES: NA.25

Properties

• biological source: crab (red)
• Quality Level: 200
• Assay: ≥99%
• form: powder
• technique(s): HPLC: suitable
• color: white to off-white
• mp: 211 °C (dec.) (lit.)
• solubility: H₂O: 50 mg/mL, clear to very slightly hazy (colorless to faint yellow solution)
• storage temp.: −20°C
• SMILES string: CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O
• InChI: 1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6-,7-,8?/m1/s1
• InChI key: OVRNDRQMDRJTHS-RTRLPJTCSA-N

Description

General description

N-acetylglucosamine (GlcNAc) is the acetylated derivative of glucosamine (GlcN). It is an important component of proteoglycans, glycoproteins, glycosaminoglycans (GAGs), and other building units found in connective tissue.

Application

N-Acetyl-D-glucosamine has been used:

• as sugar for competitive inhibition in lectin histochemistry
• as a component in Barbour-Stonner-Kelly (BSK) medium for cultivating Borrelia burgdorferi spirochetes strains
• as a component of binding buffer to suspend Streptococcus pneumoniae strains for inhibition assay to examine the specificity of M-ficolin binding to S. pneumoniae strains

Biochem/physiol Actions

N-acetylglucosamine (GlcNAc) is mainly used in the food, cosmetics, and pharmaceutical industries.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves