A9187

Adenosine 5′-triphosphate magnesium salt

≥95%, bacterial

• Synonym(s): ATP, ATP magnesium salt
• Empirical Formula (Hill Notation): C₁₀H₁₆N₅O₁₃P₃ · xMg²⁺
• CAS Number: 74804-12-9
• Molecular Weight: 507.18 (free acid basis)
• MDL number: MFCD00084767
• eCl@ss: 32160414
• PubChem Substance ID: 24891422
• NACRES: NA.51

Properties

• biological source: bacterial
• Assay: ≥95%
• form: powder
• solubility: H₂O: 50 mg/mL
• storage temp.: −20°C
• SMILES string: [Mg].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C(O)C3O
• InChI: 1S/C10H16N5O13P3.Mg.2H/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;
• InChI key: CPGAIACWYFBIFN-UHFFFAOYSA-N

Description

Application

Adenosine 5′-triphosphate magnesium salt has been used:

• as a supplement in intracellular medium for Ca²⁺ retention assay and fluorescence wide field imaging analysis
• as a component in potassium methane sulfonate-based internal solution for in vitro electrophysiology of cortical neurons
• as a component in action potential intracellular solution

Biochem/physiol Actions

Adenosine 5γ-triphosphate (ATP) is a central component of energy storage and metabolism in vivo. ATP is use in many cellular processes, respiration, biosynthetic reactions, motility, and cell division. ATP is a substrate of many kinases involved in cell signaling and of adenylate cyclase(s) that produce the second messenger cAMP. ATP provides the metabolic energy to drive metabolic pumps. ATP serves as a coenzyme in a wide array of enzymatic reactions.

P₂ purinergic agonist; increases activity of Ca²⁺-activated K⁺ channels; substrate for ATP-dependent enzyme systems

Safety Information

• Pictograms: GHS08
• Signal Word: Warning
• Hazard Statements: H371
• Precautionary Statements: P260 - P264 - P270 - P308 + P311 - P405 - P501
• Hazard Classifications: STOT SE 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable