G4875

D-(+)-Glucosamine hydrochloride

≥99%, crystalline

• Synonym(s): 2-Amino-2-deoxy-D-glucose hydrochloride, Chitosamine hydrochloride
• Empirical Formula (Hill Notation): C₆H₁₃NO₅ · HCl
• CAS Number: 66-84-2
• Molecular Weight: 215.63
• Beilstein: 4157370
• EC Number: 200-638-1
• MDL number: MFCD00135831
• PubChem Substance ID: 24895187
• NACRES: NA.25

Properties

• biological source: Aspergillus niger
• Quality Level: 200
• Assay: ≥99%
• form: crystalline
• technique(s): HPLC: suitable
• mp: 190-194 °C (dec.) (lit.)
• SMILES string: Cl.N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O
• InChI: 1S/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3-,4-,5-,6?;/m1./s1
• InChI key: QKPLRMLTKYXDST-NSEZLWDYSA-N

Description

Application

D-(+)-Glucosamine hydrochloride has been used:

• as a standard to quantify and express chitin content as glucosamine equivalents.
• to stimulate cells with glucose in the presence of glucosamine

Biochem/physiol Actions

Glucosamine, an amino sugar, is the precursor of the hexosamine biosynthetic pathway leading to the formation of UDP-N-acetylglucosamine (UDP-GlcNAc), which is then used for making glycosaminoglycans, proteoglycans, and glycolipids. D-(+)-Glucosamine inhibits the coaggregation of Candida yeast species with the bacterial strain S. salivarius.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves