M4670

D-Mannosamine hydrochloride

• Synonym(s): 2-Amino-2-deoxy-D-mannose hydrochloride
• Empirical Formula (Hill Notation): C₆H₁₃NO₅ · HCl
• CAS Number: 5505-63-5
• Molecular Weight: 215.63
• Beilstein: 3914860
• EC Number: 226-847-8
• MDL number: MFCD00064557
• PubChem Substance ID: 24896935
• NACRES: NA.25

Properties

• biological source: crab (shell); shrimp shells
• Quality Level: 200
• Assay: ≥98% (HPLC)
• form: powder
• technique(s): HPLC: suitable
• mp: 168 °C (dec.) (lit.)
• storage temp.: 2-8°C
• SMILES string: Cl[H].N[C@@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O
• InChI: 1S/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3+,4-,5-,6?;/m1./s1
• InChI key: QKPLRMLTKYXDST-OHXGPSCHSA-N

Description

Application

D-Mannosamine hydrochloride can be used for the synthesis of non-natural ManNAc analogs for the expression of thiols on cell-surface sialic acids. It has been used in a study to investigate the synthesis and high-throughput screening of N-acetyl-β-hexosaminidase inhibitor libraries targeting osteoarthritis.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable