API5
apoptosis inhibitor 5
Synonyms:
AAC-11, AAC11
Species:
Human API5 (8539), Mouse Api5 (11800), Rat Api5 (362170), Zebrafish api5 (321676), Horse API5 (100050009), domestic guinea pig Api5 (100717249), naked mole-rat Api5 (101719611), sheep API5 (101108774), Domestic Rabbit API5 (100345733), cow API5 (538968) ...More
UniProtKB ID:
Gene ID:
- Human(8539) Summary: This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
- Mouse(11800) apoptosis inhibitor 5
- Rat(362170) apoptosis inhibitor 5
- Zebrafish(321676) apoptosis inhibitor 5
- Horse(100050009) apoptosis inhibitor 5
- domestic guinea pig(100717249) apoptosis inhibitor 5
- naked mole-rat(101719611) apoptosis inhibitor 5
- sheep(101108774) apoptosis inhibitor 5
- Domestic Rabbit(100345733) apoptosis inhibitor 5
- cow(538968) apoptosis inhibitor 5
- domestic cat(101081754) apoptosis inhibitor 5
- dog(483413) apoptosis inhibitor 5
- chicken(423168) apoptosis inhibitor 5
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.