ARG1
arginase 1
Synonyms:
Species:
Human ARG1 (383), Mouse Arg1 (11846), Rat Arg1 (29221), sheep ARG1 (101122363), cow ARG1 (513608), Goat ARG1 (100860853), domestic cat ARG1 (101089865), dog ARG1 (474823), Domestic Rabbit ARG1 (100008814), Thale Cress ARG1 (843166) ...More
UniProtKB ID:
Gene ID:
- Human(383) Summary: Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
- Mouse(11846) arginase, liver
- Rat(29221) arginase, liver
- sheep(101122363) arginase, liver
- cow(513608) arginase, liver
- Goat(100860853) arginase, liver
- domestic cat(101089865) arginase, liver
- dog(474823) arginase, liver
- Domestic Rabbit(100008814) arginase, liver
- Thale Cress(843166) DnaJ-like protein ARG1
- domestic guinea pig(100730269) arginase, liver
- Zebrafish(570368) arginase, liver
- naked mole-rat(101703947) arginase, liver
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