CAST
calpastatin
Synonyms:
BS-17
Species:
Human CAST (831), Mouse Cast (12380), Rat Cast (25403), naked mole-rat Cast (101704637), Zebrafish cast (563084), domestic guinea pig Cast (100719285), cow CAST (281039), sheep CAST (443364), Domestic Rabbit CAST (100009098), dog CAST (479148) ...More
UniProtKB ID:
Gene ID:
- Human(831) Summary: The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]
- Mouse(12380) calpastatin
- Rat(25403) calpastatin
- naked mole-rat(101704637) calpastatin
- Zebrafish(563084) calpastatin
- domestic guinea pig(100719285) calpastatin
- cow(281039) calpastatin
- sheep(443364) calpastatin
- Domestic Rabbit(100009098) calpastatin
- dog(479148) calpastatin
- domestic cat(101088981) calpastatin
- Horse(100073225) calpastatin
- Goat(100861304) calpastatin
- chicken(427121) calpastatin
- fruit fly(247972) ojos castanos
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