CBS
cystathionine-beta-synthase
Synonyms:
HIP4
Species:
Human CBS (875), Mouse Cbs (12411), Rat Cbs (24250), fruit fly Cbs (5657009), fruit fly cbs (36492), fruit fly Cbs (33081), chicken CBS (418545), dog CBS (611071), cow CBS (514525), domestic cat CBS (101093038) ...More
UniProtKB ID:
Gene ID:
- Human(875) Summary: The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2010]
- Mouse(12411) cystathionine beta-synthase
- Rat(24250) cystathionine beta synthase
- fruit fly(5657009) Calcium-binding protein in Shaker
- fruit fly(36492) centrosomin's beautiful sister
- fruit fly(33081) Cystathionine beta-synthase
- chicken(418545) cystathionine-beta-synthase
- dog(611071) cystathionine-beta-synthase
- cow(514525) cystathionine-beta-synthase
- domestic cat(101093038) cystathionine-beta-synthase
- Domestic Rabbit(100008766) cystathionine-beta-synthase
- sheep(101106301) cystathionine-beta-synthase
- naked mole-rat(101703797) cystathionine-beta-synthase
- domestic guinea pig(100734876) cystathionine-beta-synthase
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