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Merck

CCL2

chemokine (C-C motif) ligand 2

Synonyms:
GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF
Species:
UniProtKB ID:
Gene ID:
  • Human(6347) Summary: This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. [provided by RefSeq, Jul 2008]
  • Mouse(20296) chemokine (C-C motif) ligand 2
  • Rat(24770) chemokine (C-C motif) ligand 2
  • dog(403981) chemokine (C-C motif) ligand 2
  • naked mole-rat(101697988) chemokine (C-C motif) ligand 2
  • Domestic Rabbit(100009130) chemokine (C-C motif) ligand 2
  • domestic guinea pig(100135494) chemokine (C-C motif) ligand 2
  • Horse(100034136) chemokine (C-C motif) ligand 2
  • cow(281043) chemokine (C-C motif) ligand 2
  • sheep(101120093) chemokine (C-C motif) ligand 2
  • sheep(100294591) chemokine (C-C motif) ligand 2

Custom & Knockdown Gene Products

ELISA

Product Number
Description
Species
Porcine CCL2 / C-C Motif Chemokine 2 ELISA Kit, ,
Species
Canine CCL2 / C-C Motif Chemokine 2 ELISA Kit, ,
Species
dog
Equine MCP-1 ELISA, for serum, plasma and cell culture supernatants,
Species
horse
Rhesus Macaque MCP-1 ELISA, for serum, plasma and cell culture supernatants,
Species
Bovine MCP-1 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
cow

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Monocyte Chemotactic Protein-1 Antibody, Chemicon®, from rabbit,
Species Reactivity
rat
Application
ELISA
neutralization

western blot

Proteins

Product Number
Description
Species
Monocyte Chemotactic Protein-1, Recombinant rat, The Macrophage/monocyte chemoattractant protein-1 (or MCP-1 protein) plays an important role in the inflammatory response of blood monocytes & tissue macrophages.,
Species
rat