Skip to Content
Merck

CES1

carboxylesterase 1

Synonyms:
ACAT, CE-1, CEH, CES2, HMSE, HMSE1, PCE-1, REH, SES1, TGH, hCE-1
Species:
UniProtKB ID:
Gene ID:
  • Human(1066) Summary: This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
  • naked mole-rat(101726140) carboxylesterase 1
  • cow(512098) carboxylesterase 1 (monocyte/macrophage serine esterase 1)
  • domestic cat(493774) carboxylesterase 1
  • dog(403643) carboxylesterase 1
  • chicken(415786) carboxylesterase 1 (monocyte/macrophage serine esterase 1)

Custom & Knockdown Gene Products

ELISA

Product Number
Description
Species
Human Carboxylesterase 1 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
1-Phenyl-1,2-propanedione, 98%, FG,
Species
human
p-Benzoquinone, reagent grade, ≥98%,
Species
human
Acetylacetone, Wacker Chemie AG, ≥99.5% (GC),
Species
human
Acetylacetone, ReagentPlus®, ≥99%,
Species
human
3-Methyl-1,2-cyclohexanedione, ≥98%, FG,
Species
human