F2
coagulation factor II (thrombin)
Synonyms:
PT, RPRGL2, THPH1
Species:
Human F2 (2147), Mouse F2 (14061), Rat F2 (29251), naked mole-rat F2 (101720561), domestic guinea pig F2 (100725988), sheep F2 (100307041), cow F2 (280685), domestic cat F2 (101090463), dog F2 (100686115), chicken F2 (395306)
UniProtKB ID:
Gene ID:
- Human(2147) Summary: Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia. [provided by RefSeq, Jul 2008]
- Mouse(14061) coagulation factor II
- Rat(29251) coagulation factor II
- naked mole-rat(101720561) coagulation factor II (thrombin)
- domestic guinea pig(100725988) coagulation factor II (thrombin)
- sheep(100307041) coagulation factor II (thrombin)
- cow(280685) coagulation factor II (thrombin)
- domestic cat(101090463) coagulation factor II (thrombin)
- dog(100686115) coagulation factor II (thrombin)
- chicken(395306) coagulation factor II (thrombin)
- Zebrafish(325881) coagulation factor II (thrombin)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Thrombin Antibody, clone GMA-020, clone GMA-020, Upstate®, from mouse,
Species Reactivity
human
Application
western blot
Anti-Prothrombin Antibody, clone GMA-095, clone GMA-095, Upstate®, from mouse,
Species Reactivity
human
Application
ELISA
western blot
western blot
Proteins
Product Number
Description
Species
Thrombin from bovine plasma, lyophilized powder, 40-500 NIH units/mg protein (biuret),
Species
cow