FA2H
fatty acid 2-hydroxylase
Synonyms:
FAAH, FAH1, FAXDC1, SCS7, SPG35
Species:
Human FA2H (79152), Mouse Fa2h (338521), Rat Fa2h (307855), fruit fly fa2h (35670), Zebrafish fa2h (792257), chicken FA2H (415687), dog FA2H (610417), naked mole-rat Fa2h (101713306), cow FA2H (516891), sheep FA2H (101116673) ...More
UniProtKB ID:
Gene ID:
- Human(79152) Summary: This gene encodes a protein that catalyzes the synthesis of 2-hydroxysphingolipids, a subset of sphingolipids that contain 2-hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structural diversity arises from modification of the hydrophobic ceramide moiety, such as by 2-hydroxylation of the N-acyl chain, and the existence of many different head groups. Mutations in this gene have been associated with leukodystrophy dysmyelinating with spastic paraparesis with or without dystonia.[provided by RefSeq, Mar 2010]
- Mouse(338521) fatty acid 2-hydroxylase
- Rat(307855) fatty acid 2-hydroxylase
- fruit fly(35670) fatty acid 2-hydroylase
- Zebrafish(792257) fatty acid 2-hydroxylase
- chicken(415687) fatty acid 2-hydroxylase
- dog(610417) fatty acid 2-hydroxylase
- naked mole-rat(101713306) fatty acid 2-hydroxylase
- cow(516891) fatty acid 2-hydroxylase
- sheep(101116673) fatty acid 2-hydroxylase
- domestic guinea pig(100734359) fatty acid 2-hydroxylase
- domestic cat(101089563) fatty acid 2-hydroxylase
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