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Merck

GLUL

glutamate-ammonia ligase

Synonyms:
GLNS, GS, PIG43, PIG59
Species:
UniProtKB ID:
Gene ID:
  • Human(2752) Summary: The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia. Glutamine is a main source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signaling. This gene is expressed during early fetal stages, and plays an important role in controlling body pH by removing ammonia from circulation. Mutations in this gene are associated with congenital glutamine deficiency. Several alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2009]
  • Mouse(14645) glutamate-ammonia ligase (glutamine synthetase)
  • Rat(24957) glutamate-ammonia ligase
  • domestic guinea pig(100715062) glutamate-ammonia ligase
  • chicken(396489) glutamate-ammonia ligase
  • Horse(100054716) glutamate-ammonia ligase
  • domestic cat(101093325) glutamate-ammonia ligase
  • dog(403443) glutamate-ammonia ligase
  • cow(281199) glutamate-ammonia ligase

Custom & Knockdown Gene Products

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Glutamine Synthetase Antibody, clone GS-6, clone GS-6, Chemicon®, from mouse,
Species Reactivity
human, mouse, rat, sheep
Application
ELISA
immunohistochemistry

western blot