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Merck

IL6

interleukin 6 (interferon, beta 2)

Synonyms:
BSF2, HGF, HSF, IFNB2, IL-6
Species:
UniProtKB ID:
Gene ID:
  • Human(3569) Summary: This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq, Jun 2011]
  • Mouse(16193) interleukin 6
  • Rat(24498) interleukin 6
  • Zebrafish(100885851) interleukin 6 (interferon, beta 2)
  • chicken(395337) interleukin 6 (interferon, beta 2)
  • dog(403985) interleukin 6 (interferon, beta 2)
  • domestic cat(493687) interleukin 6 (interferon, beta 2)
  • Horse(100034196) interleukin 6 (interferon, beta 2)
  • cow(517016) interleukin 6 (interferon, beta 2)
  • cow(280826) interleukin 6 (interferon, beta 2)
  • Goat(100860785) interleukin 6 (interferon, beta 2)
  • sheep(443406) interleukin 6 (interferon, beta 2)
  • Domestic Rabbit(100008733) interleukin 6 (interferon, beta 2)
  • naked mole-rat(101702602) interleukin 6 (interferon, beta 2)

Custom & Knockdown Gene Products

ELISA

Product Number
Description
Species
Rhesus Macaque IL6 / Interleukin-6 ELISA Kit, ,
Species
Rat Interleukin-6 ELISA Kit, for for cell lysate and tissue lysate,
Species
rat
Rat IL-6 ELISA Kit, for serum, plasma and cell culture supernatants,
Species
rat
Canine IL6 / Interleukin-6 ELISA Kit, for serum, plasma and cell culture supernatants,
Species
dog
Mouse IL-6 ELISA Kit, for cell and tissue lysates,
Species
rat

Small Molecule - Antagonist

Product Number
Description
Species
(Z)-4-Hydroxytamoxifen, ≥98% Z isomer,
Species
human, rat

Antibodies

Product Number
Description
Species Reactivity
Application
Human IL-6 Conferma® ELISA, quantification of human IL-6 in serum, plasma, or culture media samples,
Species Reactivity
human
Application
ELISA
Anti-Interleukin-6 Antibody, clone B-E8, clone B-E8, Chemicon®, from mouse,
Species Reactivity
human
Application
ELISA
flow cytometry

immunohistochemistry

neutralization