INS
insulin
Synonyms:
IDDM2, ILPR, IRDN, MODY10
Species:
Human INS (3630), Zebrafish ins (30262), chicken INS (396145), chicken INS (100327340), chicken INS (100327578), chicken INS (100310645), chicken INS (100327579), chicken INS (100327337), chicken INS (100327350), chicken INS (100309524) ...More
UniProtKB ID:
Gene ID:
- Human(3630) Summary: After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
- Zebrafish(30262) preproinsulin
- chicken(396145) insulin
- chicken(100327340) Insulin level
- chicken(100327578) Insulin level
- chicken(100310645) Insulin level
- chicken(100327579) Insulin level
- chicken(100327337) Insulin level
- chicken(100327350) Insulin level
- chicken(100309524) Insulin level
- chicken(100327347) Insulin level
- chicken(100327333) Insulin level
- dog(483665) insulin
- domestic cat(493804) insulin
- cow(280829) insulin
- Domestic Rabbit(100009181) insulin
- domestic guinea pig(100379579) insulin
- naked mole-rat(101719971) insulin
Custom & Knockdown Gene Products
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Custom Gene Products
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ELISA
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Pro-Insulin C-Peptide Antibody, clone C-PEP-01, clone C-PEP-01, from mouse,
Species Reactivity
human
Application
immunohistochemistry
Anti-Insulin Antibody, clone E11D7, clone E11D7, from mouse,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
immunohistochemistry
Proteins
Product Number
Description
Species
Insulin from bovine pancreas, γ-irradiated, BioXtra, suitable for cell culture, potency: ≥20 units/mg (USP units), lyophilized powder,
Species
cow
Insulin solution from bovine pancreas, BioReagent, 10 mg/mL insulin in 25 mM HEPES, pH 8.2, sterile-filtered, suitable for cell culture,
Species
cow