MSLN
mesothelin
Synonyms:
MPF, SMRP
Species:
Human MSLN (10232), Mouse Msln (56047), Rat Msln (60333), chicken MSLN (416534), naked mole-rat Msln (101708230), sheep MSLN (101111680), dog MSLN (611363), domestic guinea pig Msln (100722390), cow MSLN (516237), domestic cat MSLN (101091333)
UniProtKB ID:
Gene ID:
- Human(10232) Summary: This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]
- Mouse(56047) mesothelin
- Rat(60333) mesothelin
- chicken(416534) mesothelin
- naked mole-rat(101708230) mesothelin
- sheep(101111680) mesothelin
- dog(611363) mesothelin
- domestic guinea pig(100722390) mesothelin
- cow(516237) mesothelin
- domestic cat(101091333) mesothelin
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