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Merck

PPARG

peroxisome proliferator-activated receptor gamma

Synonyms:
CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma
Species:
Human PPARG (5468), Mouse Pparg (19016), Rat Pparg (25664), Zebrafish pparg (557037), chicken PPARG (373928), cow PPARG (281993), naked mole-rat Pparg (101711078), Goat PPARG (100861309), domestic cat PPARG (100049014), domestic cat PPARG (101095161) ...More
UniProtKB ID:
P37231, A8K3G6, B5BUA1, O00684, O00710, O14515, Q0QJH8, Q15178
Gene ID:
  • Human(5468) Summary: This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(19016) peroxisome proliferator activated receptor gamma
  • Rat(25664) peroxisome proliferator-activated receptor gamma
  • Zebrafish(557037) peroxisome proliferator activated receptor gamma
  • chicken(373928) peroxisome proliferator-activated receptor gamma
  • cow(281993) peroxisome proliferator-activated receptor gamma
  • naked mole-rat(101711078) peroxisome proliferator-activated receptor gamma
  • Goat(100861309) peroxisome proliferator-activated receptor gamma
  • domestic cat(100049014) peroxisome proliferator-activated receptor gamma
  • domestic cat(101095161) peroxisome proliferator-activated receptor gamma
  • domestic guinea pig(100729138) peroxisome proliferator-activated receptor gamma
  • sheep(443513) peroxisome proliferator-activated receptor gamma
  • dog(403606) peroxisome proliferator-activated receptor gamma

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Small Molecule - Agonist

Product Number
Description
Species
Y0001519
Pioglitazone for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Y0001520
Pioglitazone hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
1539905
Pioglitazone hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Species
human
CDS021593
Pioglitazone, ,
Species
human
B1115000
Bezafibrate, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
M6191
GW9662, >98% (HPLC),
Species
human
T2573
Troglitazone, ≥98% (HPLC),
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
MAB3872
Anti-PPAR γ Antibody, isoform 1&2, ascites fluid, clone 1H4, Chemicon®,
Species Reactivity
human, mouse
Application
ELISA
immunocytochemistry
western blot
MAB3632
Anti-PPAR gamma 1 and 2 Antibody, phospho-specific (Ser112), ascites fluid, Chemicon®,
Species Reactivity
human, mouse
Application
ELISA
immunocytochemistry
western blot