PPT1
palmitoyl-protein thioesterase 1
Synonyms:
CLN1, INCL, PPT
Species:
Human PPT1 (5538), Mouse Ppt1 (19063), Rat Ppt1 (29411), domestic cat PPT1 (101097408), cow PPT1 (281421), Thale Cress PPT1 (828466), fruit fly Ppt1 (31805), Zebrafish ppt1 (406648), naked mole-rat Ppt1 (101718692), sheep PPT1 (100170397) ...More
UniProtKB ID:
Gene ID:
- Human(5538) Summary: The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2008]
- Mouse(19063) palmitoyl-protein thioesterase 1
- Rat(29411) palmitoyl-protein thioesterase 1
- domestic cat(101097408) palmitoyl-protein thioesterase 1
- cow(281421) palmitoyl-protein thioesterase 1
- Thale Cress(828466) 4-hydroxybenzoate polyprenyltransferase
- fruit fly(31805) Palmitoyl-protein thioesterase 1
- Zebrafish(406648) palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)
- naked mole-rat(101718692) palmitoyl-protein thioesterase 1
- sheep(100170397) palmitoyl-protein thioesterase 1
- chicken(419681) palmitoyl-protein thioesterase 1
- sheep(101121049) palmitoyl-protein thioesterase 1
- domestic guinea pig(100720295) palmitoyl-protein thioesterase 1
- dog(475316) palmitoyl-protein thioesterase 1
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