SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
Synonyms:
GLYA, SHMT
Species:
Human SHMT2 (6472), Mouse Shmt2 (108037), Rat Shmt2 (299857), Zebrafish shmt2 (100144628), sheep SHMT2 (101101880), domestic guinea pig Shmt2 (100725949), Domestic Rabbit SHMT2 (100009293), cow SHMT2 (507197), Horse SHMT2 (100050119), domestic cat SHMT2 (101091290) ...More
UniProtKB ID:
Gene ID:
- Human(6472) Summary: This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
- Mouse(108037) serine hydroxymethyltransferase 2 (mitochondrial)
- Rat(299857) serine hydroxymethyltransferase 2 (mitochondrial)
- Zebrafish(100144628) serine hydroxymethyltransferase 2 (mitochondrial)
- sheep(101101880) serine hydroxymethyltransferase 2 (mitochondrial)
- domestic guinea pig(100725949) serine hydroxymethyltransferase 2 (mitochondrial)
- Domestic Rabbit(100009293) serine hydroxymethyltransferase 2 (mitochondrial)
- cow(507197) serine hydroxymethyltransferase 2 (mitochondrial)
- Horse(100050119) serine hydroxymethyltransferase 2 (mitochondrial)
- domestic cat(101091290) serine hydroxymethyltransferase 2 (mitochondrial)
- dog(607458) serine hydroxymethyltransferase 2 (mitochondrial)
- naked mole-rat(101721429) serine hydroxymethyltransferase 2 (mitochondrial)
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