TDO2
tryptophan 2,3-dioxygenase
Synonyms:
TDO, TO, TPH2, TRPO
Species:
Human TDO2 (6999), Mouse Tdo2 (56720), Rat Tdo2 (64206), dog TDO2 (475476), chicken TDO2 (422409), sheep TDO2 (101109739), Domestic Rabbit TDO2 (100344083), cow TDO2 (530397), Horse TDO2 (100069524), domestic cat TDO2 (101090935) ...More
UniProtKB ID:
Gene ID:
- Human(6999) Summary: This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism. [provided by RefSeq, Feb 2012]
- Mouse(56720) tryptophan 2,3-dioxygenase
- Rat(64206) tryptophan 2,3-dioxygenase
- dog(475476) tryptophan 2,3-dioxygenase
- chicken(422409) tryptophan 2,3-dioxygenase
- sheep(101109739) tryptophan 2,3-dioxygenase
- Domestic Rabbit(100344083) tryptophan 2,3-dioxygenase
- cow(530397) tryptophan 2,3-dioxygenase
- Horse(100069524) tryptophan 2,3-dioxygenase
- domestic cat(101090935) tryptophan 2,3-dioxygenase
- naked mole-rat(101711781) tryptophan 2,3-dioxygenase
- domestic guinea pig(100727713) tryptophan 2,3-dioxygenase
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