TSC2
tuberous sclerosis 2
Synonyms:
LAM, TSC4
Species:
Human TSC2 (7249), Mouse Tsc2 (22084), Rat Tsc2 (24855), domestic guinea pig Tsc2 (100731690), chicken TSC2 (416552), dog TSC2 (479883), domestic cat TSC2 (101082969), sheep TSC2 (101115088), naked mole-rat Tsc2 (101713968), Horse TSC2 (100065679) ...More
UniProtKB ID:
Gene ID:
- Human(7249) Summary: Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Mouse(22084) tuberous sclerosis 2
- Rat(24855) tuberous sclerosis 2
- domestic guinea pig(100731690) tuberous sclerosis 2
- chicken(416552) tuberous sclerosis 2
- dog(479883) tuberous sclerosis 2
- domestic cat(101082969) tuberous sclerosis 2
- sheep(101115088) tuberous sclerosis 2
- naked mole-rat(101713968) tuberous sclerosis 2
- Horse(100065679) tuberous sclerosis 2
- Goat(100860943) tuberous sclerosis 2
- cow(504985) tuberous sclerosis 2
- Zebrafish(567524) tuberous sclerosis 2
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