- Pressurized liquid extraction and liquid chromatography-tandem mass spectrometry applied to determine iodinated X-ray contrast media in sewage sludge.
Pressurized liquid extraction and liquid chromatography-tandem mass spectrometry applied to determine iodinated X-ray contrast media in sewage sludge.
Analytica chimica acta (2014-08-31)
S Echeverría, F Borrull, E Pocurull, N Fontanals
PMID25172819
ABSTRACT
Pressurized liquid extraction (PLE) has been successfully applied for the first time to the extraction of five iodinated X-ray contrast media from sludge. Once optimized all PLE parameters, the extract has been analyzed by liquid chromatography-tandem mass spectrometry, being the method developed sensible enough to reach limit of quantifications (LOQs) of 25 μg kg(-1) (d.w.). The developed method has been applied to the analysis of sludge from urban sewage treatment plants and although some compounds such as iopromide, diatrizoic acid and iopamidol have been identified, their concentrations have been lower than their LOQs.
MATERIALS
Product Number
Brand
Product Description
USP
Residual Solvent Class 2 - Acetonitrile, United States Pharmacopeia (USP) Reference Standard
Sigma-Aldrich
Dichloromethane, HPLC Plus, for HPLC, GC, and residue analysis, ≥99.9%, contains 50-150 ppm amylene as stabilizer
Sigma-Aldrich
Dichloromethane, suitable for HPLC, ≥99.9%, contains 40-150 ppm amylene as stabilizer
Sigma-Aldrich
Acetonitrile solution, contains 0.1 % (v/v) trifluoroacetic acid, suitable for HPLC