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  • Protein kinase- and lipase inhibitors of inositide metabolism deplete IP

Protein kinase- and lipase inhibitors of inositide metabolism deplete IP

Cellular signalling (2017-10-19)
Subu Surendran Rajasekaran, Christopher Illies, Stephen B Shears, Huanchen Wang, Thais S Ayala, Joilson O Martins, Elisabetta Daré, Per-Olof Berggren, Christopher J Barker
PMID29042286
ABSTRACT

Inositol pyrophosphates have emerged as important regulators of many critical cellular processes from vesicle trafficking and cytoskeletal rearrangement to telomere length regulation and apoptosis. We have previously demonstrated that 5-di-phosphoinositol pentakisphosphate, IP