Skip to Content
Merck

1.00590

Glycine

crystalline, EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, USP

Synonym(s):

Glycine, Gly, Aminoacetic acid, Aminoethanoic acid, Aminoacetic acid, Aminoethanoic acid, Glycocoll

Sign In to View Organizational & Contract Pricing.

Select a Size

1 KG

Inquire

3 KG

Inquire

5 KG

Inquire

12 KG

PLN 3,140.00

25 KG

Inquire

25 KG

PLN 5,110.00

25 KG

PLN 5,110.00

This item is not able to be purchased as a guest user. For further information, please contact us at +48 225 844 261or

.


About This Item

Linear Formula:
NH2CH2COOH
CAS Number:
Molecular Weight:
75.07
EC Index Number:
200-272-2
UNSPSC Code:
12352121
Beilstein/REAXYS Number:
635782
MDL number:

Skip To

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Glycine, crystalline, EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, USP

agency

ChP
JP
BP
Ph. Eur.
USP

SMILES string

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

vapor pressure

0.0000171 Pa ( 25 °C)

description

EMPROVE® EXPERT Ph Eur,BP,JP,USP

product line

EMPROVE® EXPERT

assay

98.5-101.0% (calculated on dried substance, perchloric acid titration)

form

crystalline
solid

technique(s)

inhibition assay: suitable

pH

5.9-6.4 (20 °C, 50 g/L in H2O)

pKa (25 °C)

(1) 2.35, (2) 9.60
2.35

mp

240 °C (dec.) (lit.)

solubility

soluble 250 g/L

density

1.161 g/cm3 at 20 °C

application(s)

liquid formulation
parenterals
pharma/biopharma processes
pharmaceutical

storage temp.

2-30°C

Quality Level

Looking for similar products? Visit Product Comparison Guide

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
PHR11111295800G5417
application(s)

liquid formulation
parenterals
pharma/biopharma processes
pharmaceutical

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

technique(s)

inhibition assay: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

cell culture | mammalian: suitable

agency

BP, JP, USP, ChP, Ph. Eur.

agency

traceable to Ph. Eur. G0450000, traceable to USP 1295800

agency

-

agency

-

form

crystalline, solid

form

-

form

-

form

crystalline powder

assay

98.5-101.0% (calculated on dried substance, perchloric acid titration)

assay

-

assay

-

assay

≥98.5%

density

1.161 g/cm3 at 20 °C

density

-

density

-

density

-

Application

Glycine is an amino acid which is used widely in the biopharma industry as stabilizer, tonicity modifier, buffer and precipitating agent. It is also used as an emollient, emulsifying agent and solubilizer in solid and semi-solid formulations.
Due to its low microbial and endotoxin limits, Glycine cryst. Emprove® Expert is especially suitable for high-risk applications.

Biochem/physiol Actions

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Disclaimer

The substance 1.00590 has no REACH registration because the only supported use is the use in medicinal products for human or veterinary use or in food or feedingstuffs according to article 2 of the REACH Regulation (EC) No 1907/2006.

General description

Chemicals play an important role in the stabilization of a biologic drug during its manufacturing and formulation process – for instance, by preventing aggregation. We offer a wide range of high-quality stabilizers, buffers and salts to successfully purify and formulate your biomolecules. Specifically developed for high-risk applications, they are low in bioburden and endotoxins.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Stay compliant with GMP using the Emprove® Program

Accelerate qualification, maintain compliance, and save time with Emprove® Dossiers.

Download Dossiers

Note: you will be brought to EmproveSuite.com. Your username and password are separate from SigmaAldrich.com and may differ.

Register for free and access Emprove® Dossiers within minutes. Upgrade your subscription plan to unlock advanced and customized content in the Emprove® Suite

Not finding what you are looking for? Visit the Emprove® Program Help page.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

This article outlines critical factors in long-term stability of proteins, and how different stabilizers protect again mechanical and thermal stress.

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service