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8.52097

Sigma-Aldrich

Fmoc-Lys(biotin)-OH

Novabiochem®

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Synonym(s):
Fmoc-Lys(biotin)-OH, N-α-Fmoc-N-ε-biotinyl-L-lysine
Empirical Formula (Hill Notation):
C31H38N4O6S
CAS Number:
Molecular Weight:
594.72
MDL number:

Quality Level

product line

Novabiochem®

Assay

≥85.0% (HPLC)
≥95% (TLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

biotin

storage temp.

2-30°C

InChI

1S/C31H38N4O6S/c36-27(15-6-5-14-26-28-25(18-42-26)33-30(39)35-28)32-16-8-7-13-24(29(37)38)34-31(40)41-17-23-21-11-3-1-9-19(21)20-10-2-4-12-22(20)23/h1-4,9-12,23-26,28H,5-8,13-18H2,(H,32,36)(H,34,40)(H,37,38)(H2,33,35,39)/t24-,25-,26-,28-/m0/s1

InChI key

OFIBQNGDYNGUEZ-OBXRUURASA-N

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Fmoc-Lys(biotin)-OH Novabiochem®

8.52097

Fmoc-Lys(biotin)-OH

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Fmoc-Lys(Dnp)-OH

Fmoc-Lys(Fmoc)-OH Novabiochem®

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Fmoc-Lys(Fmoc)-OH

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8.52096

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functional group

biotin

functional group

Fmoc

functional group

amine

functional group

Fmoc

assay

≥85.0% (HPLC), ≥95% (TLC)

assay

≥97.0% (HPLC), ≥98% (TLC)

assay

≥90.0% (acidimetric), ≥97% (TLC), ≥97.5% (HPLC)

assay

≥95.5% (HPLC), ≥97% (TLC)

product line

Novabiochem®

product line

Novabiochem®

product line

Novabiochem®

product line

Novabiochem®

storage temp.

2-30°C

storage temp.

15-25°C

storage temp.

2-30°C

storage temp.

2-8°C

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

General description

A modified lysine derivative for the preparation of biotin-labeled peptides by Fmoc SPPS.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Biotinylation Reagents for Peptide Synthesis

Application

  • Supplemental Information for: Describes the reaction of amino functionalized resin with HCTU-activated Fmoc-Lys(biotin)-OH in DMF to install a biocytin molecule. Fmoc was deprotected by 20% (K Sapkota, JK Lucas, JW Faulkner, MF Lichte, YL Guo, tandf.figshare.com).

Linkage

Replaces: 04-12-1237

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(CMA2)): ≥ 95 %
Assay (HPLC, area%): ≥ 85.0 % (a/a)
Solubility (0,1 mmole in 1 ml NMP): clearly soluble
Water (K. F.): ≤ 3.0 %
This product can contain up to 10% DMF in order to assure an ideal solubility.

To see the solvent systems used for TLC of Novabiochem® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Articles

Biotin-labelled peptides have many important applications in immunology and histochemistry, such as affinity purification and FRET-based flow cytometry, solid-phase immunoassays, and receptor localization, that exploit the high affinity of streptavidin and avidin for biotin.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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