All Photos(1)
Synonym(s):
Anti-OT, Anti-OT-NPI, Anti-OXT-NPI
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, mouse, rat, rabbit, sheep, hamster
manufacturer/tradename
Chemicon®
technique(s)
dot blot: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable (paraffin)
radioimmunoassay: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... OXTR(5021)
Specificity
Recognizes Oxytocin. Less than 1% cross-reactivity with arginine vasopressin.
Immunogen
Synthetic oxytocin (Sigma) conjugated to thyroglobulin.
Application
Anti-Oxytocin Antibody is an antibody against Oxytocin for use in DB, IC, IH(P), RIA.
Immunohistochemistry: 1:5,000-1:10,000 (18-24 hour incubation) on formalin, Bouin′s or Zamboni′s fixed tissue. Will react on paraffin embedded tissue.
Immunocytochemistry: 1:10,000 on fetal rat neurons.
Dot Blot: 1:1000
RIA
Optimal working dilutions must be determined by the end user.
Immunocytochemistry: 1:10,000 on fetal rat neurons.
Dot Blot: 1:1000
RIA
Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Hormones & Receptors
CNS Control of Metabolism
Hormones & Receptors
CNS Control of Metabolism
Physical form
Neat rabbit antisera. Liquid. Contains no preservative.
Unpurified
Storage and Stability
Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Analysis Note
Control
Pituitary Gland
Pituitary Gland
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Christine N Yohn et al.
Frontiers in behavioral neuroscience, 12, 181-181 (2018-09-14)
Natural variations in parenting are associated with differences in expression of several hormones and neuropeptides which may mediate lasting effects on offspring development, like regulation of stress reactivity and social behavior. Using the bi-parental California mouse, we have demonstrated that
Yu-Ting Lin et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 38(5), 1218-1231 (2017-12-28)
Oxytocin (OXT) receptors (OXTRs) are prominently expressed in hippocampal CA2 and CA3 pyramidal neurons, but little is known about its physiological function. As the functional necessity of hippocampal CA2 for social memory processing, we tested whether CA2 OXTRs may contribute
Nicole Denoix et al.
Frontiers in neurology, 11, 649-649 (2020-08-06)
The hydrogen sulfide (H2S) and the oxytocin/oxytocin receptor (OT/OTR) systems interact in trauma and are implicated in vascular protection and regulation of fluid homeostasis. Acute brain injury is associated with pressure-induced edema formation, blood brain barrier disruption, and neuro-inflammation. The
Haruki Nishimura et al.
Frontiers in endocrinology, 11, 43-43 (2020-03-03)
Various types of acute/chronic nociceptive stimuli cause neuroendocrine responses such as activation of the hypothalamo-neurohypophysial [oxytocin (OXT) and arginine vasopressin (AVP)] system and hypothalamo-pituitary adrenal (HPA) axis. Chronic multiple-arthritis activates the OXT/AVP system, but the effects of acute mono-arthritis on
Karin Warfvinge et al.
The journal of headache and pain, 21(1), 10-10 (2020-02-08)
Recent work, both clinical and experimental, suggests that the hypothalamic hormone oxytocin (OT) and its receptor (OTR) may be involved in migraine pathophysiology. In order to better understand possible central actions of OT in migraine/headache pathogenesis, we mapped the distribution
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