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IF011

Sigma-Aldrich

Interferon-β Protein, Recombinant mouse

Interferon-β Protein, Recombinant mouse.

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eCl@ss:
32160405

biological source

mouse

Quality Level

recombinant

expressed in E. coli

Assay

≥95%

form

liquid

manufacturer/tradename

Chemicon®

technique(s)

cell culture | mammalian: suitable

UniProt accession no.

shipped in

dry ice

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This Item
I9032I4777IF009
recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

assay

≥95%

assay

≥95%

assay

≥98% (SDS-PAGE)

assay

>95%

form

liquid

form

buffered aqueous solution

form

lyophilized powder

form

liquid

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

UniProt accession no.

P01574, P01575

UniProt accession no.

P01575

UniProt accession no.

P01580

UniProt accession no.

P01563, P01573

General description

Purified Recombinant Mouse Interferon β (IFNbeta)

Unit Definition

Specific Activity: The units are determined with respect to the international reference standard for mouse interferon beta (IFNbeta) provided by the National Institutes of Health.Unit of activity measured on mouse L929 cells with encephalomyocarditis virus (EMCV).

Analysis Note

Specific Activity: Determined by assaying inhibition of virus-induced cytopathic effect.In this antiviral assay for interferon, about 1 unit/ml of interferon is the quantity necessary to produce a cytopathic effect of 50%

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Shawn M Freed et al.
FEBS letters, 595(21), 2665-2674 (2021-10-01)
Toll-like receptor 3 (TLR3) recognizes viral double-stranded RNA (or the synthetic dsRNA analog poly I:C) and induces a signal transduction pathway that results in activation of transcription factors that induce expression of antiviral genes including type I interferon (IFN-I). Secreted
Adriana G Quiroz-Reyes et al.
Molecular medicine reports, 25(6) (2022-04-30)
As the understanding of cancer grows, new therapies have been proposed to improve the well-known limitations of current therapies, whose efficiency relies mostly on early detection, surgery and chemotherapy. Mesenchymal stem cells (MSCs) have been introduced as a promissory and
Jon B Suzich et al.
EMBO reports, 22(9), e52547-e52547 (2021-07-02)
Herpes simplex virus (HSV) establishes latent infection in long-lived neurons. During initial infection, neurons are exposed to multiple inflammatory cytokines but the effects of immune signaling on the nature of HSV latency are unknown. We show that initial infection of
Paulino Barragán-Iglesias et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 40(18), 3517-3532 (2020-04-05)
One of the first signs of viral infection is body-wide aches and pain. Although this type of pain usually subsides, at the extreme, viral infections can induce painful neuropathies that can last for decades. Neither of these types of pain

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