M3637

Supelco

Methaqualone hydrochloride

analytical standard

Synonym(s):
2-Methyl-3-(2-methylphenyl)-4(3H)-quinazolinone hydrochloride
Empirical Formula (Hill Notation):
C16H14N2O · HCl
CAS Number:
Molecular Weight:
286.76
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

form

neat

drug control

USDEA Schedule I; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada

application(s)

HPLC: suitable
gas chromatography (GC): suitable

Featured Industry

Forensics and Toxicology
Pharmaceutical (small molecule)

format

neat

SMILES string

Cl.Cc1ccccc1N2C(C)=Nc3ccccc3C2=O

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Sedative/hypnotic that displaces diazepam from its binding site on the GABAA receptor inducing cytochrome P-450 and UDP-glucuronyltransferase activity.

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Precautionary Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

UN 2811 6.1 / PGIII

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
S Buyuktimkin et al.
Journal of pharmaceutical sciences, 81(11), 1092-1094 (1992-11-01)
Locomotor activity-inhibiting, anticonvulsant, muscle relaxant, analgesic, and antimicrobial properties of 2-methyl-3-pyridinium-acetylamino-4(3H)-quinazolinone chloride (1), 2-methyl-3-(4-methylpyridinium)acetylamino-4(3H)-quinazolinone chloride (2), 2-methyl-3-(4-ethylpyridinium)acetylamino-4(3H)-quinazolinone chloride (3), 2-methyl-3-(3-carboxamidopyridinium)acetylamino-4(3H)-quinazolinon e chloride (4), and 2-methyl-3-(4-carboxamidopyridinium)-acetylamino-4(3H)- quinazolinone chloride (5) were investigated. The locomotor activity-inhibiting properties and anticonvulsant activity of 2 were...

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