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MAK445

Sigma-Aldrich

Protein Creatinine Ratio Assay Kit

Sufficient for 100 colorimetric tests

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Quality Level

100

detection method

colorimetric

relevant disease(s)

endocrinological disorders, diabetes; cardiovascular diseases, hypertension

storage temp.

2-8°C

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Protein Creatinine Ratio Assay Kit Sufficient for 100 colorimetric tests

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MAK445

Protein Creatinine Ratio Assay Kit

Creatine Kinase Activity Assay Kit sufficient for 100 tests (Ultraviolet)

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MAK116

Creatine Kinase Activity Assay Kit

Urea Colorimetric Assay Kit II sufficient for 100 colorimetric tests

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MAK410

Urea Colorimetric Assay Kit II

Free Amino Nitrogen Assay Kit Sufficient for 100 colorimetric tests

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relevant disease(s)

endocrinological disorders, diabetes; cardiovascular diseases, hypertension

relevant disease(s)

-

relevant disease(s)

-

relevant disease(s)

-

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

-

Quality Level

100

Quality Level

-

Quality Level

100

Quality Level

100

General description

Protein is filtered out of urine by the glomeruli of the kidneys. Albumin is the most common serum protein, thus the majority of the protein in urine is albumin. A damaged kidney will allow some protein through into the urine, the less protein in urine the better. Elevated protein levels in urine is called microalbuminuria or proteinuria, which typically arises due to type 1 diabetes, type 2 diabetes, or high blood pressure.

Creatinine is synthesized in the body at a fairly constant rate from creatine. In healthy individuals, creatinine secretion is independent of diet and is fairly constant. The creatinine clearance test has become one of the most sensitive tests for measuring glomerular filtration rate.

Features and Benefits

  • Sensitive and accurate. Linear detection range in 96-well plate: 1 - 20 mg/dL Protein and 1 - 150 mg/dL Creatinine.
  • Fast and convenient. No sample pre-treatment is needed. Simple 10- minute "add-incubate-read" procedure.
  • Compatible with high-throughput handling systems.

Suitability

The kit is suitable for the quantitative determination of urinary protein and creatinine concentrations (protein/creatinine ratio, UPCR) in urine samples.

Principle

Protein/Creatinine Ratio (PCR) remains the simplest and most convenient test for proteinuria. Other methods such as the 24-hour urine test or timed urine test require strict adherence to sample collection protocol. Since the protein concentration is normalized to creatinine secretion, the urine sample can be taken at any time and no diet or liquid restrictions are necessary for sample collection.

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2 - STOT SE 2

Storage Class Code

8A - Combustible, corrosive hazardous materials

WGK

WGK 2

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