Merck
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RDD001

Sigma-Aldrich

Guanidine hydrochloride

anhydrous, free-flowing, Redi-Dri, ≥99%

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Synonym(s):
Aminoformamidine hydrochloride, Aminomethanamidine hydrochloride, Guanidinium chloride
Linear Formula:
NH2C(=NH)NH2 · HCl
CAS Number:
Molecular Weight:
95.53
Beilstein:
3591990
EC Number:
MDL number:
PubChem Substance ID:

grade

anhydrous

Quality Level

product line

Redi-Dri

Assay

≥99%

quality

free-flowing

pH

(25 °C, 4.6 - 6/573 g/L)

mp

180-185 °C (lit.)

solubility

H2O: 6 M

density

1.3 g/cm3 (lit.)

absorption

≤0.10 at 260 nm in H2O at 6 M

SMILES string

Cl[H].NC(N)=N

InChI

1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H

InChI key

PJJJBBJSCAKJQF-UHFFFAOYSA-N

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This Item
50940G9284G4505
product line

Redi-Dri

product line

-

product line

-

product line

-

assay

≥99%

assay

≥99.0% (AT)

assay

-

assay

≥99% (titration)

mp

180-185 °C (lit.)

mp

180-185 °C (lit.)

mp

-

mp

180-185 °C (lit.)

solubility

H2O: 6 M

solubility

H2O: 6 M at 20 °C, clear, colorless

solubility

-

solubility

H2O: 6 M

density

1.3 g/cm3 (lit.)

density

1.3 g/cm3 (lit.)

density

1.18 g/mL at 25 °C (lit.)

density

1.3 g/cm3 (lit.)

Application

Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.

Legal Information

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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