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Streptavidin from Streptomyces avidinii

essentially salt-free, lyophilized powder, ≥13 units/mg protein

CAS Number:
MDL number:


essentially salt-free, lyophilized powder

Quality Level

specific activity

≥13 units/mg protein

mol wt

~60 kDa


4 mol/mol (Biotin)


research pathology

storage temp.


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General description

Streptavidin derives its name from its bacterial source Streptomyces avidinii and from the hen egg-white protein, avidin, which has high affinity to biotin. Its homologous core shares 33% sequence similarity with avidin, as well as sharing a common tetrameric structure.[1] It is a crystalline tetrameric protein, with a molecular weight of 4*15000Da. It binds four molecules of biotin.[2][3] Streptavidin lacks carbohydrate and sulfur-containing amino acids.[4]
Streptavidin is a crystalline protein isolated from the bacterium Streptomyces avidinii and possesses biotin-binding ability. It has four binding sites for biotin like avidin and binds four molecules of biotin. Streptavidin is now considered as a new type of biotin-binding protein.[5][3]


Streptavidin from Streptomyces avidinii has been used:
  • in wire functionalization[6]
  • in streptavidin capture enzyme-linked immunosorbent assay (ELISA)[7]
  • in microbubble preparation[8]


5, 10 mg in glass bottle

Preparation Note

Affinity purified.


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

13 - Non Combustible Solids



Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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Product Information Sheet

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