SAB4501395

Anti-Acetyl-CoA Carboxylase, N-Terminal antibody produced in rabbit

affinity isolated antibody

• Synonym(s): ACAC, ACACA, ACC-α, ACCA, Acetyl-CoA carboxylase 1
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 265 kDa
• species reactivity: mouse, rat, human
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:5000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI accession no.: Q13085
• UniProt accession no.: Q13085
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... ACACA(31)

Description

General description

Anti-Acetyl-CoA Carboxylase Antibody detects endogenous levels of total Acetyl-CoA Carboxylase protein.

Acetyl-CoA carboxylase 1 (ACC1) is a cytosolic enzyme. It is located on human chromosome 17q12.

Immunogen

The antiserum was produced against synthesized peptide derived from human Acetyl-CoA Carboxylase.

Immunogen Range: 46-95

Biochem/physiol Actions

Acetyl-CoA carboxylase 1 (ACC1) catalyzes the rate-limiting step in de novo fatty acid biosynthesis. Acetyl-CoA is carboxylated to malonyl-CoA with the help of acetyl-CoA carboxylase (ACACA) in the fatty acid synthesis pathway. ACC1 is essential for the assembly of invadopodia.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable