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Merck

SRP0466

Sigma-Aldrich

BRDT (22-138) His tag human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

Synonym(s):

BRD6, CT9, bromodomain, testis-specific

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100 μG
PLN 2,640.00

PLN 2,640.00


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About This Item

UNSPSC Code:
12352200
NACRES:
NA.32

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biological source

human

recombinant

expressed in E. coli

Assay

≥90% (SDS-PAGE)

form

aqueous solution

mol wt

14.9 kDa

packaging

pkg of 100 μg

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... BRDT(676)

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This Item
SRP0448SRP0450SRP0455
recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

biological source

human

biological source

human

biological source

human

biological source

human

assay

≥90% (SDS-PAGE)

assay

≥90% (SDS-PAGE)

assay

≥90% (SDS-PAGE)

assay

≥88% (SDS-PAGE)

form

aqueous solution

form

aqueous solution

form

aqueous solution

form

aqueous solution

UniProt accession no.

Q58F21

UniProt accession no.

O95696

UniProt accession no.

P25440

UniProt accession no.

Q15059

Gene Information

human ... BRDT(676)

Gene Information

human ... BRD1(23774)

Gene Information

human ... BRD2(6046)

Gene Information

human ... BRD3(8019)

General description

Human Bromodomain testis-specific protein, also known as BRDT, BRD6, and CT9 (GenBank Accession No. NM_207189) amino-acids 22 – 138 with N-terminal HIS-tag, MW = 14.9 kDa, expressed in an E. coli expression system.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Binyamin D Berkovits et al.
Developmental biology, 360(2), 358-368 (2011-10-25)
Mice homozygous for a mutation (Brdt(∆BD1/∆BD1)) lacking the first bromodomain of Brdt, a testis-specific member of the BET family of double-bromodomain containing proteins, are sterile and exhibit profound defects in chromatin remodeling during spermiogenesis. We have now observed that a
Enyuan Shang et al.
Development (Cambridge, England), 134(19), 3507-3515 (2007-08-31)
Brdt is a testis-specific member of the distinctive BET sub-family of bromodomain motif-containing proteins, a motif that binds acetylated lysines and is implicated in chromatin remodeling. Its expression is restricted to the germ line, specifically to pachytene and diplotene spermatocytes

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