Halogenation Reagents

AlkylFluor structure – a halogenation reagent

Halogenation is fundamental tool in the organic chemist's toolbox for replacing a hydrogen atom with a halogen atom (fluorine, chlorine, bromide, or iodine). The use of halogenation reagents in various coupling protocols (e.g., Suzuki, Stille, Sonogashira) and nucleophilic substitution is prevalent and has been reported in the scientific community.

While several synthetic methods for the introduction of a halogen exist, there is still a need for efficient and practical methods for introducing other halogen-containing structural elements, in particular at a late-stage in synthesis (esp. with high yields and under mild conditions). Our readily available halogenation reagents may be used in many stages of your synthesis, and many are practical for use in late-stage development.

Our portfolio includes halogenation reagents for brominations, chlorinations, fluorinations, haloborations, and iodinations. With products such as AlkylFluor, XtalFluor®, PhenoFluor™, and PyFluor there are bench-stable reagent options for deoxyfluorination. We are dedicated to supporting all your explorations with our halogenated substrates.


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