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PKA & PKG
Our offers many products related to PKA & PKG for your research needs.
Tubulin
Tubulin is the major building block of microtubules. This intracellular cylindrical filamentous structure is present in almost all eukaryotic cells.
Complement Proteins
Application Index: Complement Proteins offered by Sigma-alderich online.The complement system is a complex cascade involving proteolytic cleavage of serum glycoproteins often activated by cell receptors. This cascade ultimately results in induction of the inflammatory response, phagocyte chemotaxis and opsonization, and
Drug Conjugate Analysis using β-Glucuronidases
Drug conjugate analysis and the enzymatic hydrolysis of glucuronides
Decorin
Decorin is a small proteoglycan, which has been found associated with collagen fibrils in all connective tissues. In the skeletal system it is found primarily in the extracellular matrix of articular cartilage, which covers the surface of adult bones in
Horseradish Peroxidase (HRP) Enzymes
Discover our peroxidase from horseradish enzymes, products, substrates, and inhibitors for your ELISA, immunoassay, and protein application needs.
Excitatory Amino Acid Transporters
Sigma-Aldrich offers many products related to excitatory amino acid transporters for your research needs.
Phospholipase D
Phosphatidylcholine (PC)-specific phospholipase D (PLD) enzymes catalyze the hydrolysis of PC to generate choline and phosphatidic acid. These enzymes belong to a superfamily of phosphatidyltransferases with a characteristic unique duplicated catalytic domain motif, the PLD or " HKD"
Matrix Metalloproteinases
Enzyme Explorer Product Application Index for Matrix Metalloproteinases enzymes offered in our online catalog.
Enzymes for Alternative Energy Research
We are committed to help unlock the today’s challenge of releasing the energy of glucose that nature has cleverly locked into lignocellulosic biomass. To the untrained eye, starch and cellulose structures appear almost identical. Yet the barriers between cellulosic biomass
Phosphodiesterases
Cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and/or cGMP. There are 11 different mammalian PDE families.
HMG-CoA Reductase (HMGR) Assay Kit
3-hydroxy-3-methylglutaryl-CoA reductase (HMGR) is a transmembrane glycoprotein, located on the endoplasmic reticulum.
Protein Kinase C (PKC)
Protein kinase C (PKC) is an AGC kinase that phosphorylates serine and threonine residues in many target proteins.
Neurotensin Receptors
Neurotensin is a 13 amino acid regulatory peptide found mainly in gut and brain. Intestinal neurotensin is produced by a discrete population of endocrine cells (N cells) scattered throughout the jejuno-ileal mucosa.
Phospholipase C
The hydrolysis of a minor membrane phospholipid, phosphatidylinositol 4,5-bisphosphate (PIP2) by a specific phospholipase C (PLC) is one of the earliest key events in the regulation of various cell functions by more than 100 extracellular signaling molecules.
G Proteins (Heterotrimeric)
Heterotrimeric G proteins, comprising α, β and γ subunits, respond to extracellular signals generated by activated seven-transmembrane (7TM) receptors by modulating intracellular effector proteins such as enzymes and ion channels.
Neuropeptidases
We offers many products related to neuropeptidases for your research needs.
Glycobiology - Carbohydrate Enzymes and Proteins
Explore our complex carbohydrate proteins, enzyme products and kits for investigating oligosaccharides, polysaccharides, and numerous additional aspects of your carbohydrate workflow.
Mucins, Glycosylated Proteins, Properties & Diagram
Mucins are a diverse family of densely glycosylated proteins. Mucin domains within the protein core are rich in threonine, serine and hydroxyproline enabling post-translational O-glycosylation.
Enzymatic Assay of Proteinase K with Hemoglobin Substrate
Proteinase K (EC 3.4.21.64) activity can be measured spectrophotometrically using hemoglobin as the substrate. Proteinase K hydrolyzes hemoglobin denatured with urea, and liberates Folin-postive amino acids and peptides. One unit will hydrolyze hemoglobin to produce color equivalent to 1.0 μmol
Enzymatic Assay of Cathepsin B
This procedure applies to all products that have a specification for Cathepsin B activity determined by the liberation of 7-amino-4-methylcoumarin from Z-Arg-Arg 7-amido-4-methylcoumarin.
Enzymatic Assay of Chitosanase from Streptomyces Species
To standardize a procedure for determining the enzymatic activity of Chitosanase.
β Secretase (BACE1) Activity Assay for BACE1 Inhibitor Screening
In recent years, the biological processes involved in the pathogenesis of Alzheimer’s disease (AD) have become increasingly better understood. It is now recognized that a key role is played by BACE1 proteases that cleave amyloid precursor protein (APP) to produce
Enzymatic Method for Determining Amylase Activity (Amylase Activity Assay)
Assay protocol for the colorimetricdetection of amylase activity in biological samples using the Amylase Activity assay kit.
Aprotinin
While aprotinin and bovine pancreatic trypsin inhibitor (BPTI) are the same protein sequence, the term aprotinin is typically used when describing the protein derived from bovine lung.
Bioluminescent Firefly Luciferase Assays
Firefly luciferase is a widely used bioluminescent reporter for studying gene regulation and function. It is a very sensitive genetic reporter due to the absence of endogenous luciferase activity in mammalian cells or tissues.
How to Work with Enzymes Supplied as Ammonium Sulfate Suspensions
Instructions for working with enzymes supplied as ammonium sulfate suspensions
Dipeptidyl Peptidase IV
Native DPPIV is a ubiquitous type II transmembrane glycoprotein and a serine protease of the S9 prolyl-oligopeptidase family. In vivo, it is synthesized with a signal peptide which functions as the membrane anchoring domain.
InsR
We offers many products related to InsR for your research needs.
Enzyme Commission Numbers
Complete List of Enzyme Commission Numbers for metabolics research.
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