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gecko

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Samantha L Payne et al.
Journal of morphology, 278(3), 380-389 (2017-01-13)
Unique among amniotes, many lizards are able to self-detach (autotomize) their tail and then regenerate a replacement. Tail regeneration involves the formation of a blastema, an accumulation of proliferating cells at the site of autotomy. Over time, cells of the...
Gregory S Watson et al.
Acta biomaterialia, 21, 109-122 (2015-03-17)
Geckos, and specifically their feet, have attracted significant attention in recent times with the focus centred around their remarkable adhesional properties. Little attention however has been dedicated to the other remaining regions of the lizard body. In this paper we...
Hirohumi Suzuki et al.
The Journal of veterinary medical science, 82(4), 408-413 (2020-02-11)
The distribution pattern of chemokine CXCL14-immunoreactive cells was examined by immunohistochemistry in the pituitary of the gecko Hemidactylus platyurus. Immunoreactive cells were observed in the pars intermedia and pars distalis of the pituitary, but not in the pars nervosa. All...
Yu-Xia Wang et al.
Journal of ethnopharmacology, 155(3), 1583-1588 (2014-08-06)
Gecko, a kind of reptile, has been widely used as a traditional Chinese medicine to treat various diseases including cancer in China for thousands of years. The aim of this study was to investigate the anti-tumor effect of AG (aqueous...
Jae-Kang Kim et al.
Beilstein journal of nanotechnology, 10, 1-8 (2019-01-27)
Splitting a large contact area into finer, sub-contact areas is thought to result in higher adaptability to rough surfaces, stronger adhesion, and a more uniform stress distribution with higher tolerance to defects. However, while it is widely believed that contact...
Domenico Fulgione et al.
Scientific reports, 9(1), 1288-1288 (2019-02-06)
The Wall Gecko shows heterogeneous colour pattern, which may vary among individuals, depending on the time of day and on the habitat segregation. Nocturnal pale geckos live exclusively on walls. Diurnal dark geckos preferentially live on olive tree trunks, demonstrating...
Rebecca P McDonald et al.
Scientific reports, 8(1), 9648-9648 (2018-06-27)
Although lizards are often described as having robust neurogenic abilities, only a handful of the more than 6300 species have been explored. Here, we provide the first evidence of homeostatic neurogenesis in the leopard gecko (Eublepharis macularius). We focused our...
Alyssa Y Stark et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(16), 6340-6345 (2013-04-12)
Although we now have thousands of studies focused on the nano-, micro-, and whole-animal mechanics of gecko adhesion on clean, dry substrates, we know relatively little about the effects of water on gecko adhesion. For many gecko species, however, rainfall...
Casey A Gilman et al.
PloS one, 10(9), e0134604-e0134604 (2015-09-04)
One of the central controversies regarding the evolution of adhesion concerns how adhesive force scales as animals change in size, either among or within species. A widely held view is that as animals become larger, the primary mechanism that enables...
Eraqi R Khannoon et al.
Journal of anatomy, 237(3), 504-519 (2020-06-03)
Tarentola annularis is a climbing gecko with a wide distribution in Africa north of the equator. In the present paper, we describe the development of the osteocranium of this lizard, from the first appearance of the cranial elements up to...
Peter Loskill et al.
Journal of the Royal Society, Interface, 10(78), 20120587-20120587 (2012-09-21)
Surface energies are commonly used to determine the adhesion forces between materials. However, the component of surface energy derived from long-range forces, such as van der Waals forces, depends on the material's structure below the outermost atomic layers. Previous theoretical...
Eraqi R Khannoon et al.
EvoDevo, 6, 8-8 (2015-04-17)
The limb and autopodium are frequently employed to study pattern formation during embryonic development, providing insights into how cells give rise to complex anatomical structures. With regard to the differentiation of structures at the distal tips of digits, geckos constitute...
Kai Yan et al.
The Journal of comparative neurology, 518(17), 3409-3426 (2010-07-01)
Geckos use vocalizations for intraspecific communication, but little is known about the organization of their central auditory system. We therefore used antibodies against the calcium-binding proteins calretinin (CR), parvalbumin (PV), and calbindin-D28k (CB) to characterize the gecko auditory system. We...
David William Green et al.
Scientific reports, 7, 41023-41023 (2017-01-26)
The external epithelial surfaces of plants and animals are frequently carpeted with small micro- and nanostructures, which broadens their adaptive capabilities in challenging physical habitats. Hairs and other shaped protuberances manage with excessive water, light contaminants, predators or parasites in...
Kirstin S Brink et al.
Frontiers in physiology, 12, 576816-576816 (2021-05-21)
Many reptiles are able to continuously replace their teeth through life, an ability attributed to the existence of epithelial stem cells. Tooth replacement occurs in a spatially and temporally regulated manner, suggesting the involvement of diffusible factors, potentially over long...
Eraqi R Khannoon
Journal of experimental zoology. Part B, Molecular and developmental evolution, 324(5), 450-464 (2015-06-10)
Studying the in ovo mode of development of squamates has the advantage of allowing easy access to embryos without surgically compromising gravid females. Despite the non-ophidian squamates being a very diverse lineage of reptiles, embryonic tables for individuals of this...
P J Werten et al.
Proceedings of the National Academy of Sciences of the United States of America, 97(7), 3282-3287 (2000-03-22)
Eye lenses of various diurnal geckos contain up to 12% iota-crystallin. This protein is related to cellular retinol-binding protein type I (CRBP I) but has 3,4-didehydroretinol, rather than retinol, as a ligand. The 3,4-didehydroretinol gives the lens a yellow color...
Spontaneous chromosomal alteraion in cell lines of poikilothermic origin (Gekko gecko).
M M Cohen et al.
Cytogenetics, 7(1), 16-26 (1968-01-01)
Fei Liu et al.
World journal of gastroenterology, 14(25), 3990-3996 (2008-07-09)
To investigate the anti-tumor effect of Chinese medicine Gecko on human esophageal carcinoma cell lines and xenografted sarcoma 180 in Kunming mice and its mechanism. The serum pharmacological method was used in vitro. The growth rates of the human esophageal...
Wafaa I M Alturk et al.
Journal of experimental zoology. Part B, Molecular and developmental evolution, 334(5), 294-310 (2020-05-16)
Studying reptilian embryonic development provides answers to many questions related to the development of tetrapods. Reptilian skin has been recently considered in studies at the evo-devo level. The lizard epidermis has to be shed periodically. At the embryonic level, contention...
Steeves Buckland et al.
PloS one, 9(6), e93387-e93387 (2014-06-26)
Genetic structure can be a consequence of recent population fragmentation and isolation, or a remnant of historical localised adaptation. This poses a challenge for conservationists since misinterpreting patterns of genetic structure may lead to inappropriate management. Of 17 species of...
Derivatives of gecko cathelicidin-related antioxidant peptide facilitate skin wound healing.
Cai, et al.
European Journal of Pharmacology, 890, 173649-173649 (2020)
Kornsorn Srikulnath et al.
PloS one, 10(8), e0134829-e0134829 (2015-08-05)
The Hokou gecko (Gekko hokouensis: Gekkonidae, Gekkota, Squamata) has the chromosome number 2n = 38, with no microchromosomes. For molecular cytogenetic characterization of the gekkotan karyotype, we constructed a cytogenetic map for G. hokouensis, which retains the ancestral karyotype of...
E A B Gilbert et al.
The Journal of comparative neurology, 526(2), 285-309 (2017-10-06)
As for many lizards, the leopard gecko (Eublepharis macularius) can self-detach its tail to avoid predation and then regenerate a replacement. The replacement tail includes a regenerated spinal cord with a simple morphology: an ependymal layer surrounded by nerve tracts....
Lorenzo Alibardi
Journal of experimental zoology. Part B, Molecular and developmental evolution, 334(5), 263-279 (2020-07-06)
The formation of the complex pattern of setae in adhesive pads of geckos and anoline lizards has been analyzed by ultrastructural, autoradiographic, and immunohistochemical methods. Setae terminate with spatulated ends responsible for adhesion that allow these lizards to climb vertical...
Andrea Aparicio Ramirez et al.
Journal of experimental zoology. Part A, Ecological and integrative physiology, 335(1), 86-95 (2020-06-03)
Crested geckos (Correlophus ciliatus, formerly Rhacodactylus ciliatus) were rediscovered in New Caledonia 25 years ago and despite being common in the pet trade, there is no published information on their physiology. We measured thermoregulation (preferred body temperature, thermal set-point range...
Yun Gu et al.
PloS one, 10(5), e0127663-e0127663 (2015-05-29)
Glial scar formation is a major obstacle to regeneration after spinal cord injury. Moreover, it has been shown that the astrocytic response to injury differs between species. Gekko japonicas is a type of reptile and it shows differential glial activation...
Ophir Shalem et al.
Science (New York, N.Y.), 343(6166), 84-87 (2013-12-18)
The simplicity of programming the CRISPR (clustered regularly interspaced short palindromic repeats)-associated nuclease Cas9 to modify specific genomic loci suggests a new way to interrogate gene function on a genome-wide scale. We show that lentiviral delivery of a genome-scale CRISPR-Cas9...
Ophir Shalem et al.
Science (New York, N.Y.), 343(6166), 84-87 (2013-12-18)
The simplicity of programming the CRISPR (clustered regularly interspaced short palindromic repeats)-associated nuclease Cas9 to modify specific genomic loci suggests a new way to interrogate gene function on a genome-wide scale. We show that lentiviral delivery of a genome-scale CRISPR-Cas9...
Kendall R Sanson et al.
Nature communications, 9(1), 5416-5416 (2018-12-24)
The creation of genome-wide libraries for CRISPR knockout (CRISPRko), interference (CRISPRi), and activation (CRISPRa) has enabled the systematic interrogation of gene function. Here, we show that our recently-described CRISPRko library (Brunello) is more effective than previously published libraries at distinguishing...
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